Specialists call for mandatory physical activity in oncology

Specialists state that physical exercise must be mandatory in cancer treatment, not optional. Evidence from studies highlights benefits like reduced cardiac toxicity and fatigue. The recommendation was emphasized at the Onco in Rio congress in Rio de Janeiro.

At the Onco in Rio congress, hosted by Rede D’Or in Rio de Janeiro, experts argued that physical exercise should be mandatorily prescribed for cancer patients. Physician Marina Rondinelli, an anesthesiologist and pain medicine specialist, stated: "Physical exercise is no longer an option; it is a prescription".

A study published in July 2025 in the British Journal of Sports Medicine, reviewing 80 articles, found that physical activity significantly reduces cardiac toxicity, cognitive impairment, and neuropathy in cancer patients. It also modulates body composition and biomarkers like insulin and C-reactive protein, while improving sleep quality, psychological well-being, and social interaction.

Rondinelli noted that 75% of chemotherapy patients experience cognitive impairment, such as memory and concentration issues, and 80% report muscle fatigue. Exercises like walking, weight training, and functional training alleviate fatigue, while aerobic and strength exercises benefit cognition. Even one minute of daily exercise is better than none, tailored to the patient's condition.

National Comprehensive Cancer Network data show 59% of patients in active treatment experience pain, rising to 64% in advanced cases and 33% in remission.

Oncologist Paulo Hoff emphasized that such prescriptions are not yet widespread, but strong evidence—like a study of 800 patients where the exercise group had half the cancer recurrences compared to the non-exercise group—matches chemotherapy's impact. Yoga is effective for sleep disturbances in women with breast cancer.

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Realistic illustration showing a woman exercising joyfully, equating exercise to therapy and antidepressants for depression relief per Cochrane review.
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Exercise can ease depression symptoms about as much as therapy, Cochrane review finds

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An updated Cochrane review of randomized trials suggests exercise can reduce depressive symptoms compared with no treatment and may perform about as well as psychological therapy. Results were also similar to antidepressants, though the evidence there is less certain, and researchers say larger, higher-quality studies are still needed.

Researchers at Newcastle University have found that just 10 minutes of intense exercise can release molecules into the bloodstream that promote DNA repair and inhibit bowel cancer cell growth. The study, involving 30 older adults, showed significant genetic changes in cancer cells exposed to post-exercise blood. These findings suggest exercise could inspire new cancer therapies.

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A new analysis suggests that varying exercise routines, such as mixing running, cycling, and swimming, may reduce mortality risk by 19 percent compared to less diverse workouts, even when total activity levels are similar. Researchers examined data from over 110,000 U.S. participants tracked for more than three decades. The findings highlight potential benefits of exercise variety, though they remain suggestive rather than conclusive.

At the National Institute of Oncology and Radiobiology (INOR), doctors and families fight childhood cancer despite limitations from the economic blockade. Survival rates remain comparable to those in developed countries due to the team's determination. Yet, shortages of medicines and supplies impact daily treatments.

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A large-scale international study has found that long-term exposure to fine particulate air pollution substantially reduces the protective effect of regular physical activity against premature death. Drawing on data from more than 1.5 million adults across several countries, the research shows that exercise’s life-extending benefits are markedly weaker in areas with high levels of PM2.5 pollution, underscoring the importance of cleaner air to maximise health gains.

Researchers from Weill Cornell Medicine and Wake Forest University School of Medicine have identified a stress-response pathway in immune cells that is activated by chemotherapy and leads to painful nerve damage. In mice, blocking this pathway with a drug already in early-stage cancer trials reduced signs of nerve injury, and a small patient study suggests a blood test might one day predict who is most at risk.

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Each year, more than 110,000 people in Colombia receive a cancer diagnosis, according to estimates from the Global Cancer Observatory. Early detection and reducing risk factors could prevent 30% to 50% of cases, the World Health Organization indicates. In Cali, Latin America's oldest cancer registry highlights the importance of prevention.

 

 

 

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