Gene Editing
Gene Therapy Advances for Genetic Conditions
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New gene therapies are in development for conditions like follistatin-related disorders and other genetic issues, aiming to provide effective treatments without ongoing interventions. The pipeline includes therapies for muscle growth, hormone regulation, and tissue repair. This marks progress in precision medicine for rare and chronic diseases.
Startup revives human embryo gene editing
Seven years after the 2018 revelation of the first gene-edited babies, biotech startup Manhattan Genomics is seeking to edit human embryos to create disease-free children. The initiative draws on CRISPR technology previously used by Chinese scientist He Jiankui. This development reignites debates in the field of genetics.
Scientists develop retron-based gene editing for multiple mutations
Researchers at The University of Texas at Austin have created a new gene-editing technique using bacterial retrons that corrects multiple disease-causing mutations simultaneously. This method targets complex genetic disorders like cystic fibrosis and improves efficiency over traditional tools. The breakthrough, published in Nature Biotechnology, offers hope for more inclusive therapies.
MIT refines prime editing to reduce gene therapy errors
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Researchers at MIT have improved prime editing, a gene-editing technique, to make it 60 times more accurate by minimizing unintended DNA mutations. This advancement could enhance the safety of treatments for genetic diseases. The study, led by Vikash Chauhan, was published in Nature.