Medicine
CPD gene mutations tied to congenital hearing loss; lab tests point to arginine and sildenafil as potential interventions
Heather Vogel Image generated by AI Fact checked
An international team reports that rare mutations in CPD (carboxypeptidase D) cause a congenital, sensorineural form of hearing loss by disrupting arginine–nitric oxide signaling in inner‑ear hair cells. In models, arginine supplementation or sildenafil partially reversed disease‑related defects, highlighting a pathway for future therapies.
Study identifies aerobic exercise as top relief for knee osteoarthritis
A comprehensive review of over 200 studies has determined that aerobic exercises such as walking, cycling, and swimming provide the most effective pain relief and mobility improvements for people with knee osteoarthritis. Published in The BMJ, the analysis emphasizes aerobic activity as the foundation of treatment. All tested exercise types proved safe, with no increased adverse events compared to controls.
Wegovy provides heart benefits even with minimal weight loss
A major trial has shown that the weight-loss drug Wegovy reduces cardiovascular risks independently of weight loss. The benefits apply even to those with mild obesity. Researchers analyzed data from over 17,000 participants to reach this conclusion.
Actor Satish Shah undergoes kidney transplant
Veteran Indian actor Satish Shah has undergone a kidney transplant following a history of dialysis and a heart procedure. Medical experts affirm that such transplants are safe when performed at reputable centers, boasting a success rate of around 98 percent. The procedure raises broader questions about kidney disease treatment in India.
Flatworm stem cells respond to distant cues, study finds
Heather Vogel Fact checked
Planarian flatworms regenerate lost body parts using stem cells steered by signals from far‑off tissues rather than nearby neighbors, research published in Cell Reports on October 15, 2025, suggests—reframing how niches regulate stem cells and hinting at future approaches to tissue repair.
Magnetic gel aids efficient kidney stone removal in pig tests
October 25, 2025 06:14British woman survives 38 years after heart-lung transplant
October 23, 2025 13:56New DNA-based therapy reduces cholesterol by nearly 50 percent
October 22, 2025 18:01Vitamin D supplements slow telomere shortening in new study
October 22, 2025 08:42New guidelines identify effective diets for chronic constipation
October 21, 2025 17:43Scientists uncover early brain damage before MS symptoms
October 20, 2025 00:01Retinal implant restores reading vision for patients with dry AMD
October 19, 2025 00:14Study finds GLP-1 drugs may slow alcohol effects
October 19, 2025 00:14EMBL researchers unveil SDR-seq for decoding disease-linked DNA
October 19, 2025 00:14Cleveland Clinic study shows surgery outperforms GLP-1 drugs for obesity and diabetes
Weight-loss drugs show early promise for alcohol and other addictions, review finds
Heather Vogel Image generated by AI Fact checked
Medications such as semaglutide (marketed as Ozempic/Wegovy) could aid treatment of alcohol and other substance use disorders, according to a peer‑reviewed review in the Journal of the Endocrine Society. Early animal and human data suggest these GLP‑1 receptor agonists act on brain reward circuits; lead author Lorenzo Leggio urged caution, saying, “Early research in both animals and humans suggests that these treatments may help reduce alcohol and other substance use.”
Reptile urine crystals may inform future approaches to gout and kidney stones
Heather Vogel Fact checked
Scientists reporting in the Journal of the American Chemical Society examined solid urine from more than 20 reptile species and found tiny uric‑acid spheres that package waste while conserving water. The study, highlighted by the American Chemical Society and ScienceDaily, also suggests uric acid helps convert toxic ammonia into a less harmful solid, a mechanism that could guide future strategies against gout and kidney stones.
Electrical stimulation reprograms human immune cells to spur repair
Heather Vogel Fact checked
Trinity College Dublin researchers report that electrically stimulating human macrophages shifted them toward an anti‑inflammatory, tissue‑repairing state in laboratory tests, pointing to potential therapies for injuries and inflammatory disease. The peer‑reviewed findings appear in Cell Reports Physical Science.
WHO reports sharp rise in antibiotic resistance
Antibiotic resistance has surged globally, outpacing treatment options, according to a new World Health Organization report. One in six lab-confirmed bacteria in 2023 resisted antibiotics, linked to common diseases. The trend poses a growing threat to public health.
Stanford implant restores reading vision for macular degeneration patients
A tiny wireless chip implanted in the eye, combined with smart glasses, has enabled many patients with advanced age-related macular degeneration to regain reading ability. In a clinical trial led by Stanford Medicine, 27 out of 32 participants achieved functional vision within a year. The findings, published in the New England Journal of Medicine, mark the first prosthetic device to provide form vision.