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Illustration of nitric oxide signaling modifying TSC2 protein to activate mTOR pathway in autism models, based on Hebrew University study.
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Study links nitric oxide to mTOR overactivity in some autism-related models

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Researchers at the Hebrew University of Jerusalem report that increased nitric oxide signaling can chemically modify the protein TSC2, reducing its levels and allowing the mTOR pathway to become overactive—a chain of events they say appears in laboratory models and in samples from some children diagnosed with autism spectrum disorder.

Police in Upshur County, West Virginia, arrested Joshua Vincent Moore and Kayla Spruill on child neglect charges after discovering their 4-year-old nonverbal child with autism locked alone in a bedroom during a domestic violence response. The incident unfolded on March 5 when the couple's 18-year-old daughter called 911. The child was found naked and covered in blue stains, attempting to use feces as paint.

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A seven-year-old autistic boy named Sebastian celebrated his birthday with a fully themed party centered on his special interest in UPS, complete with packages, balloons, and a custom cake. His mother, Jenny Grant, shared a video of the event on TikTok, which quickly went viral as viewers appreciated the creative nod to her son's passion. The local UPS store contributed materials to make the celebration authentic.

Researchers at Nagoya University in Japan have developed miniature brain models using stem cells to study interactions between the thalamus and cortex. Their work reveals the thalamus's key role in maturing cortical neural networks. The findings could advance research into neurological disorders like autism.

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A large umbrella review of research on complementary, alternative and integrative medicine (CAIM) for autism has found no high-quality evidence that any of the approaches improves core or associated autism symptoms, while also reporting that safety outcomes are rarely evaluated. The researchers also launched a public online platform intended to make the evidence easier to explore.

In Cali, Francisco Sadoct Alzate Jaramillo has founded Soccer4All Lab, a free therapeutic soccer project for children with special cognitive abilities. Inspired by protests at his medical center in 2024, the engineer and sports enthusiast combines sports and therapeutic methodologies to promote smiles and social development. It currently serves 25 children with conditions like autism and Down syndrome.

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Among people with clinically normal hearing, intellectual ability strongly predicted how well they understood speech amid competing voices, according to a peer-reviewed study from University of Washington researchers.

 

 

 

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