Illustration of nitric oxide signaling modifying TSC2 protein to activate mTOR pathway in autism models, based on Hebrew University study.
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Study links nitric oxide to mTOR overactivity in some autism-related models

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Researchers at the Hebrew University of Jerusalem report that increased nitric oxide signaling can chemically modify the protein TSC2, reducing its levels and allowing the mTOR pathway to become overactive—a chain of events they say appears in laboratory models and in samples from some children diagnosed with autism spectrum disorder.

A man and woman in Indiana face charges after allegedly allowing the man's autistic brother to suffer severe neglect in a filthy home, where blankets stuck to open wounds on his feet.

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Heather Lynn Cross and Darcy Ronald Cross have been charged with second-degree murder in the death of their 10-year-old autistic daughter, Cecilia Cross. The girl died in August 2025 after being left unattended in a safety bed that collapsed and crushed her. The couple previously faced manslaughter charges and now also face fraud allegations.

Looksmaxxing influencer Clavicular was arrested Thursday on a misdemeanor battery charge after police claimed he instigated a fight between two women during a stream. Sources close to him insist he did nothing wrong and was just standing awkwardly due to his autism. He's also under investigation for shooting at a dead alligator.

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Police in Upshur County, West Virginia, arrested Joshua Vincent Moore and Kayla Spruill on child neglect charges after discovering their 4-year-old nonverbal child with autism locked alone in a bedroom during a domestic violence response. The incident unfolded on March 5 when the couple's 18-year-old daughter called 911. The child was found naked and covered in blue stains, attempting to use feces as paint.

Researchers at the University of Birmingham used facial motion capture to compare how autistic and non-autistic adults produce facial expressions of anger, happiness and sadness, finding consistent differences in which facial features were emphasized. The work, published in *Autism Research*, suggests some misunderstandings about emotion may stem from mismatched expressive “styles” across groups rather than a one-sided problem.

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Mattel has introduced its first Barbie doll designed specifically for children on the autism spectrum, featuring noise-canceling headphones, a fidget spinner, and a communication tablet. The doll was developed in collaboration with the Autistic Self Advocacy Network to promote inclusion in toys. It is now available for purchase at major retailers.

 

 

 

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