Study associates toxic people with accelerated biological aging

A study funded by the U.S. National Institute on Aging concludes that interacting with problematic people accelerates biological aging. Each additional such person increases biological age by about nine months and speeds up the aging rate by 1.5%.

The study surveyed more than 2,000 people on the prevalence of problematic people in their lives. It then measured their biological age and aging rate using DNA patterns in saliva samples. Findings show that interacting with individuals who cause problems or complications is associated with faster biological aging. Each additional “molestia” in a person's life adds approximately nine months to their biological age. Those with more problematic people aged faster; for each additional one, their aging rate accelerated by 1.5% and increased their biological age by nine months. Biological age measures the organism's real aging, unlike chronological age, which counts time since birth. It has long been known that positive relationships prevent cognitive decline and delay biological aging. Researchers emphasize the importance of minimizing exposure to people who generate high stress and conflicts.

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Illustration of a woman with depression symptoms overlaid with microscopic view of aging monocytes in blood, linking to study on women with and without HIV.
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Study links monocyte “biological aging” in blood to emotional depression symptoms in women with and without HIV

በAI የተዘገበ በ AI የተሰራ ምስል እውነት ተፈትሸ

A study of 440 participants from the Women’s Interagency HIV Study found that accelerated epigenetic aging in monocytes—an immune cell type—tracked more closely with emotional and cognitive depression symptoms such as hopelessness and loss of pleasure than with physical symptoms like fatigue. The work, published in The Journals of Gerontology: Series A, adds evidence that cell-type-specific aging measures could contribute to future biological tools to complement symptom-based depression screening, though researchers say more validation is needed before clinical use.

A Yale University study has found that nearly half of adults age 65 and older showed measurable improvements in cognitive function, physical function, or both over a period of up to 12 years. The research draws on data from more than 11,000 participants and links positive age beliefs to these gains. It challenges the view that aging always involves decline.

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Researchers at Edith Cowan University have proposed that positive travel experiences could help slow some signs of aging. By applying the theory of entropy to tourism, they argue it supports the body's balance and resilience. The findings appear in a 2024 study published in the Journal of Travel Research.

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