Women’s verbal memory may delay alzheimer’s diagnosis by years

Women maintain normal scores on standard memory tests for nearly three years longer than men even after Alzheimer’s-related brain changes begin. This cognitive advantage can mask early signs of the disease and delay treatment. A new analysis of long-term studies in the US and Canada highlights the issue.

Researchers led by Sasha Novozhilova at McGill University examined data from older adults who underwent regular cognitive tests and brain scans. Participants recalled lists of 15 words in immediate, delayed, and distracted conditions. Women with significant amyloid buildup in their brains continued to score normally for an average of 2.7 years longer than men with comparable pathology.

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Elderly woman describing a picture in a lab with speech pauses indicated, related to cognitive study
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Pauses and filler words in picture descriptions were linked to executive function in a Baycrest-led study

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Small speech timing habits—such as silent pauses, “um” and “uh,” and difficulty finding words—were associated with performance on standard executive-function tests in a study by researchers at Baycrest, the University of Toronto and York University.

New research from the University of California San Diego shows that several common dementia risk factors affect women's cognitive performance more strongly than men's. The findings help explain why women account for nearly two thirds of Alzheimer's cases in the United States.

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People who reported more mentally stimulating experiences from childhood through older age were less likely to develop Alzheimer’s disease and tended to develop symptoms years later than peers with the lowest enrichment, according to an observational study published in Neurology.

A University of California San Francisco study has linked lower but still normal levels of active vitamin B12 to slower thinking and white matter damage in healthy older adults. The research, published in Annals of Neurology in 2025, suggests current guidelines may miss early neurological risks. Researchers examined 231 participants with an average age of 71.

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A study of over 375,000 Finns has linked hospital treatment for severe infections like cystitis and pneumonia to a higher risk of developing dementia within five to six years. Researchers identified 29 conditions associated with at least a 20 percent increased risk, with infections playing a key role. The findings suggest that preventing such infections could help modify dementia risk.

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