Ingatan verbal wanita mungkin tunda diagnosis alzheimer selama bertahun-tahun

Wanita mempertahankan skor normal pada tes ingatan standar hampir tiga tahun lebih lama daripada pria, bahkan setelah perubahan otak terkait Alzheimer mulai terjadi. Keunggulan kognitif ini dapat menutupi tanda-tanda awal penyakit tersebut dan menunda pengobatan. Analisis baru terhadap studi jangka panjang di AS dan Kanada menyoroti masalah ini.

Para peneliti yang dipimpin oleh Sasha Novozhilova di McGill University memeriksa data dari orang dewasa lanjut usia yang menjalani tes kognitif dan pemindaian otak secara berkala. Peserta diminta mengingat daftar 15 kata dalam kondisi segera, tertunda, dan terdistraksi. Wanita dengan penumpukan amiloid yang signifikan di otak mereka tetap mendapatkan skor normal rata-rata 2,7 tahun lebih lama daripada pria dengan patologi serupa.

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A scientist in a lab analyzing a blood sample for early Alzheimer's detection, with brain scan overlays.
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Blood test can reveal Alzheimer's signs years ahead

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A new study shows that blood tests can detect signs of Alzheimer's several years before the disease develops. American researchers published the findings in The Lancet.

New research from the University of California San Diego shows that several common dementia risk factors affect women's cognitive performance more strongly than men's. The findings help explain why women account for nearly two thirds of Alzheimer's cases in the United States.

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People who reported more mentally stimulating experiences from childhood through older age were less likely to develop Alzheimer’s disease and tended to develop symptoms years later than peers with the lowest enrichment, according to an observational study published in Neurology.

Small speech timing habits—such as silent pauses, “um” and “uh,” and difficulty finding words—were associated with performance on standard executive-function tests in a study by researchers at Baycrest, the University of Toronto and York University.

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An 83-year-old woman with severe Alzheimer’s disease began speaking in full sentences and regained bladder control after taking a large dose of psilocybin. The changes occurred following a single session with the psychedelic compound derived from magic mushrooms. Researchers describe the case as dramatic but stress it is only one anecdotal report.

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