女性はアルツハイマー病に関連する脳の変化が始まった後でも、男性より約3年長く標準的な記憶テストで正常なスコアを維持することがわかりました。この認知上の優位性が疾患の初期兆候を覆い隠し、治療を遅らせる可能性があります。米国とカナダで実施された長期研究の新たな分析がこの問題を指摘しています。
マギル大学のサーシャ・ノヴォジロヴァ氏らが率いる研究チームは、定期的な認知検査と脳スキャンを受けた高齢者のデータを分析しました。参加者は、即時記憶、遅延記憶、および妨害下での記憶の状態において、15個の単語リストを想起しました。脳内に有意なアミロイド蓄積が見られる女性は、同程度の病理を持つ男性と比較して、平均で2.7年長く正常なスコアを維持していました。
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Small speech timing habits—such as silent pauses, “um” and “uh,” and difficulty finding words—were associated with performance on standard executive-function tests in a study by researchers at Baycrest, the University of Toronto and York University.
New research from the University of California San Diego shows that several common dementia risk factors affect women's cognitive performance more strongly than men's. The findings help explain why women account for nearly two thirds of Alzheimer's cases in the United States.
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People who reported more mentally stimulating experiences from childhood through older age were less likely to develop Alzheimer’s disease and tended to develop symptoms years later than peers with the lowest enrichment, according to an observational study published in Neurology.
A University of California San Francisco study has linked lower but still normal levels of active vitamin B12 to slower thinking and white matter damage in healthy older adults. The research, published in Annals of Neurology in 2025, suggests current guidelines may miss early neurological risks. Researchers examined 231 participants with an average age of 71.
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A study of over 375,000 Finns has linked hospital treatment for severe infections like cystitis and pneumonia to a higher risk of developing dementia within five to six years. Researchers identified 29 conditions associated with at least a 20 percent increased risk, with infections playing a key role. The findings suggest that preventing such infections could help modify dementia risk.