Close-up photo of graying hair with overlaid stem cells, illustrating study on stress links to graying and melanoma.

Study links graying hair and melanoma to stress responses in pigment stem cells

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Japanese researchers report that hair graying and melanoma can arise from the same melanocyte stem cells, which take different paths depending on DNA damage and local signals. Published online October 6, 2025 in Nature Cell Biology, the University of Tokyo-led study outlines a protective differentiation program that promotes graying and how carcinogens can subvert it to favor melanoma.

Online brain training tied to decade‑equivalent boost in cholinergic function, McGill trial finds

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A double‑blind McGill University–led clinical trial reports that 10 weeks of BrainHQ exercises increased a PET marker of cholinergic function in healthy older adults by an amount the authors say roughly offsets about a decade of age‑related decline. The peer‑reviewed study used a specialized tracer to confirm the biochemical change.

Endurance exercise improves immune function in older adults

A new study reveals that decades of endurance exercise, such as running and cycling, may keep the immune system youthful and resilient in older adults. Researchers found that natural killer cells in trained individuals functioned better, showed lower inflammation, and resisted fatigue under stress. The findings suggest physical activity trains the immune system much like it does muscles.

Scientists reverse brain aging in mice using stem cells

Researchers at Cedars-Sinai have developed young immune cells from human stem cells that reversed signs of aging and Alzheimer's disease in mice. The treatment improved memory and brain structure in the animals. The findings, published in Advanced Science, suggest potential for personalized therapies against cognitive decline.

A healthy adult engaging in a long continuous walk in a park, illustrating the link between extended walking bouts and reduced cardiovascular risk.

Longer continuous walks linked to sharply lower heart risk, study finds

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Walking in bouts of 10–15 minutes or longer was associated with substantially lower cardiovascular risk among adults taking fewer than 8,000 steps a day, with 15‑minute‑plus bouts tied to about a two‑thirds lower risk than very short walks, according to research published in Annals of Internal Medicine.

Study links gum disease to greater white matter changes in the brain

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Research published October 22, 2025, in Neurology® Open Access reports that older adults with gum disease had more white matter hyperintensities—a marker of tissue damage—than peers without gum disease, even after accounting for other risks.

mRNA Therapy Restores Ovarian Function

A synthetic mRNA therapy successfully regenerated uterine lining in clinical trials, engineering pathways to restore ovarian function in aging populations, as reported on September 8, 2025.

Study debunks link between calcium supplements and dementia

New research from Australian universities shows that calcium supplements do not increase dementia risk in older women. The findings, based on a long-term study of over 1,400 participants, counter earlier concerns about cognitive effects. Experts say the results reassure users taking calcium for osteoporosis prevention.

Study finds life-expectancy gains slowed after 1939

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An analysis of 23 high‑income countries published in PNAS finds the rapid longevity gains of the early 20th century have slowed markedly for cohorts born after 1939, and none of those cohorts are projected to average 100 years of life.

Evolution may explain why women outlive men

A new study suggests that the evolution of menopause plays a key role in women's longer lifespans compared to men. Researchers propose that post-reproductive life in women allows investment in grandchildren, contrasting with men's continued reproduction. This theory draws on data from hunter-gatherer societies and modern populations.

 

 

 

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