Aging

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Microscopic view contrasting helpful and harmful senescent cells in tissue repair
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Review argues some “senescent” cells can support tissue repair, complicating anti-aging strategies

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A review in the journal Aging (Aging-US) says senescent cells—often dubbed “zombie cells”—can contribute to wound healing and tissue stability in some settings, even as other senescent cells promote inflammation and age-related disease.

A new perspective article in Frontiers in Nutrition argues that public health advice on protein intake and physical activity is largely designed to prevent deficiency, and that many people may benefit from aiming above today’s minimum recommendations to support strength, independence and cognitive function as they age.

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A Yale University study has found that nearly half of adults age 65 and older showed measurable improvements in cognitive function, physical function, or both over a period of up to 12 years. The research draws on data from more than 11,000 participants and links positive age beliefs to these gains. It challenges the view that aging always involves decline.

Researchers at Texas A&M University have developed a nasal spray that appears to reverse aspects of brain aging after just two doses. The treatment reduced inflammation and restored memory function in models for months afterward. The findings were published in the Journal of Extracellular Vesicles.

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A 2023 study found that falling levels of the protein Menin in the hypothalamus drive multiple signs of aging in mice. Restoring the protein or supplementing with the amino acid D-serine improved memory and other measures.

A University of Connecticut-led clinical trial found that older women recovering from a recent hip fracture who used a topical testosterone gel alongside a structured exercise program did not experience the typical rise in visceral abdominal fat seen during recovery. Researchers followed participants for six months and assessed body composition with imaging scans.

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Researchers at Edith Cowan University have proposed that positive travel experiences could help slow some signs of aging. By applying the theory of entropy to tourism, they argue it supports the body's balance and resilience. The findings appear in a 2024 study published in the Journal of Travel Research.

 

 

 

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