Aging

Sundin
Elderly man at dental exam with overlaid brain scan illustrating gum disease's link to brain white matter changes.

Study links gum disease to greater white matter changes in the brain

Heather Vogel Larawang ginawa ng AI Fact checked

Research published October 22, 2025, in Neurology® Open Access reports that older adults with gum disease had more white matter hyperintensities—a marker of tissue damage—than peers without gum disease, even after accounting for other risks.

Online brain training tied to decade‑equivalent boost in cholinergic function, McGill trial finds

Heather Vogel Fact checked

A double‑blind McGill University–led clinical trial reports that 10 weeks of BrainHQ exercises increased a PET marker of cholinergic function in healthy older adults by an amount the authors say roughly offsets about a decade of age‑related decline. The peer‑reviewed study used a specialized tracer to confirm the biochemical change.

Northwestern study uncovers why superagers retain youthful memories

Researchers at Northwestern University have spent 25 years studying SuperAgers—people over 80 with memories as sharp as those 30 years younger—revealing key brain traits that resist cognitive decline. Their findings, published in a new perspective article, highlight two protective mechanisms against Alzheimer's-related damage and emphasize the role of social connections. The work could lead to new strategies for preventing dementia.

Scientists reverse brain aging in mice using stem cells

Researchers at Cedars-Sinai have developed young immune cells from human stem cells that reversed signs of aging and Alzheimer's disease in mice. The treatment improved memory and brain structure in the animals. The findings, published in Advanced Science, suggest potential for personalized therapies against cognitive decline.

A healthy adult engaging in a long continuous walk in a park, illustrating the link between extended walking bouts and reduced cardiovascular risk.

Longer continuous walks linked to sharply lower heart risk, study finds

Heather Vogel Larawang ginawa ng AI Fact checked

Walking in bouts of 10–15 minutes or longer was associated with substantially lower cardiovascular risk among adults taking fewer than 8,000 steps a day, with 15‑minute‑plus bouts tied to about a two‑thirds lower risk than very short walks, according to research published in Annals of Internal Medicine.

USC scientists measure brain's microvascular pulses linked to Alzheimer's

Researchers at the University of Southern California have developed the first noninvasive method to capture the rhythmic pulsing of the brain's tiniest blood vessels. Using advanced 7T MRI, they found these pulses strengthen with age and hypertension, potentially disrupting waste clearance and contributing to Alzheimer's disease. The findings, published in Nature Cardiovascular Research, could lead to new biomarkers for neurodegenerative conditions.

Study links graying hair and melanoma to stress responses in pigment stem cells

Heather Vogel Fact checked

Japanese researchers report that hair graying and melanoma can arise from the same melanocyte stem cells, which take different paths depending on DNA damage and local signals. Published online October 6, 2025 in Nature Cell Biology, the University of Tokyo-led study outlines a protective differentiation program that promotes graying and how carcinogens can subvert it to favor melanoma.

mRNA Therapy Restores Ovarian Function

A synthetic mRNA therapy successfully regenerated uterine lining in clinical trials, engineering pathways to restore ovarian function in aging populations, as reported on September 8, 2025.

Study finds life-expectancy gains slowed after 1939

Heather Vogel Fact checked

An analysis of 23 high‑income countries published in PNAS finds the rapid longevity gains of the early 20th century have slowed markedly for cohorts born after 1939, and none of those cohorts are projected to average 100 years of life.

Study shows harmful sperm mutations rise with men's age

New research reveals that genetic mutations in men's sperm, which can lead to diseases in offspring, increase with age due to evolutionary selection within the testes. Scientists used advanced sequencing to analyze sperm from 81 men aged 24 to 75, finding that harmful mutations affect 2 percent of sperm in early 30s men but rise to 4.5 percent in 70-year-olds. The findings, published October 8 in Nature, highlight risks for future generations.

 

 

 

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