Study links common IBS drugs to higher long-term death risk

16 апреля 2026

Сообщено ИИ

Researchers at Cedars-Sinai analyzed nearly 20 years of health records from over 650,000 U.S. adults with irritable bowel syndrome, finding associations between certain medications and increased mortality. Antidepressants were linked to a 35% higher risk of death, while loperamide and diphenoxylate showed about double the risk compared to non-users. Other IBS treatments like FDA-approved drugs and antispasmodics showed no such increase.

The study, published in Communications Medicine, examined long-term safety of treatments for IBS, a chronic condition affecting about 10% of Americans. Led by Ali Rezaie, MD, medical director of the GI Motility Program at Cedars-Sinai, the research filled a gap left by short-term clinical trials, which typically last less than a year despite patients often using medications for decades. Rezaie noted, 'Many patients are diagnosed with IBS at a young age and may remain on medications for years.'

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Illustration of a man using a smartphone on the toilet, highlighting a study's link to increased hemorrhoid odds.

Study finds smartphone use on the toilet is associated with higher odds of hemorrhoids

8 марта 2026 Сообщено ИИ Изображение, созданное ИИ Проверено фактами

A small study of adults undergoing screening colonoscopy found that people who reported using smartphones while sitting on the toilet were more likely to have hemorrhoids detected during the procedure. The research, published in PLOS One, also found phone users spent longer on the toilet than non-users, though the authors cautioned the results show an association rather than proof that phones cause the condition.

Study links early childhood stress to lifelong digestive problems

A new study in Gastroenterology connects early life stress to long-term gut issues through disruptions in gut-brain communication. Mouse experiments and large human cohorts show links to pain, constipation, and irritable bowel syndrome. Researchers suggest targeted treatments based on specific biological pathways.

Genetic study links vitamin B1 to bowel movement frequency

22 января 2026 Сообщено ИИ

A new genetic analysis has identified key DNA regions influencing how often people have bowel movements, with a surprising link to vitamin B1. Researchers analyzed data from over 268,000 individuals and found that higher thiamine intake correlates with more frequent stools, depending on genetic variations. The findings, published in Gut, suggest new pathways for studying gut disorders like irritable bowel syndrome.

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Doctor hunts for top-quality stool donors in Boston

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Chemotherapy alters gut bacteria to block cancer metastasis

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UK study finds risperidone raises stroke risk in dementia patients

Study: Insomnia and obstructive sleep apnea together are linked to sharply higher hypertension and heart disease risk in post-9/11 veterans

A Yale School of Medicine-led study of nearly 1 million post-9/11 U.S. veterans found that people diagnosed with both insomnia and obstructive sleep apnea had substantially higher rates of new-onset hypertension and cardiovascular disease than those with only one of the conditions.

Severe infections raise dementia risk in large Finnish study

24 марта 2026 Сообщено ИИ

A study of over 375,000 Finns has linked hospital treatment for severe infections like cystitis and pneumonia to a higher risk of developing dementia within five to six years. Researchers identified 29 conditions associated with at least a 20 percent increased risk, with infections playing a key role. The findings suggest that preventing such infections could help modify dementia risk.

India today investigation reveals lax drug norms for weight loss injections

An investigation by India Today highlights how weak enforcement of regulations allows easy access to prescription-only weight-loss drugs in India, leading to increased misuse.

09 апреля 2026, 23:54