Personalized Medicine
Gut methane may shape how many calories people absorb from fiber, ASU study finds
Heather Vogel Image generated by AI Fact checked
Arizona State University researchers report that people who produce more methane in the gut tend to extract more metabolizable energy from a fiber‑rich diet, pointing to microbiome differences that could inform personalized nutrition. The work appears in The ISME Journal (2025) and was highlighted by ASU on October 24, 2025.
EMBL researchers unveil SDR-seq for decoding disease-linked DNA
Scientists at the European Molecular Biology Laboratory (EMBL) have developed SDR-seq, a new tool that simultaneously analyzes DNA and RNA in single cells. This innovation targets non-coding DNA regions, where over 95% of disease-associated genetic variants are located. The method promises to enhance understanding of complex diseases like heart disease, autism, and lymphoma.
Scientists create mini human livers to predict drug toxicities
Researchers at Cincinnati Children's Hospital Medical Center and Roche have developed a human liver organoid microarray platform that models immune-driven drug reactions. This system, built from patient-derived stem cells and immune cells, accurately replicates toxicities like those from flucloxacillin in genetically susceptible individuals. The findings were published online on September 26, 2025, in Advanced Science.
Lancet review questions gluten as main driver of most ‘gluten sensitivity’ symptoms
Heather Vogel Fact checked
A University of Melbourne–led review published in The Lancet on October 22, 2025, argues that many symptoms attributed to non‑coeliac gluten sensitivity are more often linked to FODMAPs, other wheat components, and gut–brain interactions than to gluten itself. The authors call for better diagnostics, individualized care, and a shift away from unnecessary gluten avoidance.
Finnish study shows omega-3 benefits vary by individual
A new Finnish study reveals that the omega-3 fatty acid eicosapentaenoic acid (EPA) from fish oil affects metabolism differently in each person, with benefits appearing quickly but fading soon after supplementation stops. Researchers observed significant variations in blood lipid profiles among healthy adults taking high doses. The findings emphasize the role of personalized approaches in cardiovascular health.
Bacteria in tumors produce molecule to boost cancer chemotherapy
Reported by AI
Scientists have identified a molecule produced by bacteria inside tumors that enhances the effectiveness of chemotherapy against colorectal cancer. The compound, 2-methylisocitrate, damages cancer cell DNA and disrupts their metabolism. This discovery could lead to new treatments that make existing drugs more potent.