Medical Imaging
Cryo-expansion microscopy captures 3D architecture of killer T cells at the immune synapse, including in human tumors
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Researchers from the University of Geneva and Lausanne University Hospital report they have visualized, in three dimensions and under near-native conditions, how cytotoxic T cells organize their killing machinery at the immune synapse. The work, published in Cell Reports, applies cryo-expansion microscopy to human T cells and to tumor tissue samples, providing nanoscale views intended to support immunology and cancer research.
Researchers at MIT have discovered that chaotic laser light can self-organize into a highly focused pencil beam, enabling 3D imaging of the blood-brain barrier 25 times faster than current methods. The technique allows real-time observation of drugs entering brain cells without fluorescent tags. This breakthrough could speed up development of treatments for neurological diseases like Alzheimer's and ALS.
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A study published March 24, 2026 in *Radiology* reports that AI-generated “deepfake” X-rays can be convincing enough to mislead radiologists and several multimodal AI systems. In testing, radiologists’ average accuracy rose from 41% when they were not told fakes were included to 75% when they were warned, highlighting potential risks for medical imaging security and clinical decision-making.
Researchers at the University of Surrey have developed an AI system that predicts a patient's knee X-ray appearance one year ahead, aiding in osteoarthritis management. The tool generates visual forecasts and risk scores, presented at MICCAI 2025. It promises faster, more transparent predictions for better patient care.
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Researchers at the University of Southern California have developed the first noninvasive method to capture the rhythmic pulsing of the brain's tiniest blood vessels. Using advanced 7T MRI, they found these pulses strengthen with age and hypertension, potentially disrupting waste clearance and contributing to Alzheimer's disease. The findings, published in Nature Cardiovascular Research, could lead to new biomarkers for neurodegenerative conditions.