Medical Imaging
University of Tokyo team debuts ‘Great Unified Microscope’ for label-free micro-to-nano cell imaging
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Researchers at the University of Tokyo have built a bidirectional, label-free microscope that captures micro- and nanoscale activity in living cells without dyes. Nicknamed the “Great Unified Microscope,” the system combines forward- and back-scattered light detection to broaden what scientists can see inside cells, including changes during cell death and estimates of particle size and refractive index.
Researchers have developed a non-invasive imaging tool called fast-RSOM that visualizes the body's smallest blood vessels through the skin. This technology identifies early microvascular endothelial dysfunction, a precursor to cardiovascular disease, allowing for earlier interventions. The portable device could integrate into routine checkups to improve heart health outcomes.
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A New York man has filed a lawsuit against Prenuvo, claiming its $2,500 whole-body MRI scan failed to detect a critical artery narrowing that led to his massive stroke months later. Sean Clifford argues that early intervention could have prevented his severe disabilities. The case highlights ongoing debates about the reliability of elective full-body scans.