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Study links uneven PARP inhibitor exposure in ovarian tumors to lysosomal drug “reservoirs”
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Researchers say they have identified a cellular mechanism that may help explain why PARP inhibitors can affect tumor cells unevenly: in lab-grown slices of human ovarian tumors, some of these drugs accumulated inside lysosomes, forming slow-release stores that created patchy drug distribution across tissue and even between neighboring cells. The findings were reported in a 2026 paper in Nature Communications.
Nagbuka ng kanyang personal na laban kontra kanser at adbokasiya para sa pagkakapantay-pantay ng kasarian sa hudikatura si Supreme Court Associate Justice Maria Filomena Singh sa isang panayam ng Rappler. Ito ay bahagi ng kanyang Rappler Talk episode na pinapalabas noong March 27. Bilang co-chairperson ng komite sa gender responsiveness, itinataguyod niya ang mas maayos na pagtrato sa mga kababaihang nasasakdal.
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A new poll reveals that nearly half of U.S. adults do not know processed meat is linked to higher colorectal cancer risk. Conducted by the Physicians Committee for Responsible Medicine and Morning Consult, the survey of 2,202 adults from February 9 to 11, 2026, found strong support for warning labels after respondents learned of the connection. Experts highlight the need for better education amid rising cases in younger adults.
The Kenyan government has raised the Social Health Authority's oncology treatment package from Ksh550,000 to Ksh800,000 per patient. Interior Principal Secretary Raymond Omollo announced the increase on March 16, 2026, amid public outcry over treatment costs. The package covers diagnosis, chemotherapy, radiotherapy, brachytherapy, surgical interventions, palliative care, consumables, and specialised imaging like PET/CT scans and MRIs at contracted facilities.
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Researchers tested a redesigned CD40 agonist antibody, 2141-V11, by injecting it directly into tumors of 12 patients with metastatic cancers. Six patients saw tumor shrinkage, with two achieving complete remission, including effects on untreated tumors elsewhere in the body. The trial reported only mild side effects, unlike prior CD40 therapies.
Researchers at Uppsala University are launching a new treatment study to help young adults who have had cancer address issues related to sexuality and fertility. Around 40 participants aged 18-39 are involved in a 12-week internet-based program. The study is expected to include a total of about 250 people.
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Researchers at Oregon Health & Science University have created a molecule called SU212 that blocks a key enzyme in triple-negative breast cancer cells. In mouse models, the compound reduced tumor growth and metastasis. The findings offer potential new treatment options for this hard-to-treat form of the disease.
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