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Early University of Calgary trial tests high-dose niacin as add-on treatment for glioblastoma
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Researchers at the University of Calgary are studying whether high doses of vitamin B3 (niacin) can improve outcomes for patients with newly diagnosed glioblastoma when added to standard treatment. An interim analysis of 24 patients found a higher-than-expected six‑month progression‑free survival rate, though investigators stress the results are preliminary and require ongoing safety monitoring.
Researchers have used genetically modified phages to harness pre-existing vaccine immunity and destroy cancer cells in mice. The approach eradicated tumors in 44 percent of treated animals with no recurrence after a year.
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A study has identified how an existing medication could improve immunotherapy outcomes for fibrolamellar carcinoma. The rare liver cancer currently has no cure and often spreads before detection. Researchers demonstrated the approach using patient tumor samples.
A Phase II randomized trial found that a six-week, home-based walking and resistance program improved attention test performance and reduced reports that others noticed cognitive problems among patients receiving chemotherapy. Low-dose ibuprofen improved some attention measures but showed mixed results on memory outcomes. The study was published in Cancer.
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New cases of lung cancer among women in Hong Kong have increased by 20 percent over the past two decades. Experts point to genetic factors and cooking fumes as contributors alongside smoking.
Cancer cases in Hong Kong have more than doubled since 1983, yet the age-standardised death rate has nearly halved to 71.1 per 100,000 people by 2023.
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New research from Fox Chase Cancer Center shows that melanoma spreads more aggressively in middle-aged mice than in young or very old ones. The pattern appears linked to changes in a specific type of immune cell over time.
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