Fluorescence micrograph illustrating uneven PARP inhibitor accumulation in lysosomes of ovarian tumor cells, creating patchy drug exposure.
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Study links uneven PARP inhibitor exposure in ovarian tumors to lysosomal drug “reservoirs”

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Researchers say they have identified a cellular mechanism that may help explain why PARP inhibitors can affect tumor cells unevenly: in lab-grown slices of human ovarian tumors, some of these drugs accumulated inside lysosomes, forming slow-release stores that created patchy drug distribution across tissue and even between neighboring cells. The findings were reported in a 2026 paper in Nature Communications.

마리아 필로메나 싱 대법관이 래플러와의 인터뷰에서 자신의 암 투병 과정과 사법부 내 성평등을 위한 옹호 활동에 관해 이야기했다. 3월 27일 '래플러 토크(Rappler Talk)'를 통해 방영된 이 인터뷰에서, 싱 대법관은 사법부 성인지 위원회 공동 의장으로서 여성들을 위해 사법 체계의 개혁을 추진하고 있다고 밝혔다.

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A new poll reveals that nearly half of U.S. adults do not know processed meat is linked to higher colorectal cancer risk. Conducted by the Physicians Committee for Responsible Medicine and Morning Consult, the survey of 2,202 adults from February 9 to 11, 2026, found strong support for warning labels after respondents learned of the connection. Experts highlight the need for better education amid rising cases in younger adults.

The Kenyan government has raised the Social Health Authority's oncology treatment package from Ksh550,000 to Ksh800,000 per patient. Interior Principal Secretary Raymond Omollo announced the increase on March 16, 2026, amid public outcry over treatment costs. The package covers diagnosis, chemotherapy, radiotherapy, brachytherapy, surgical interventions, palliative care, consumables, and specialised imaging like PET/CT scans and MRIs at contracted facilities.

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Researchers tested a redesigned CD40 agonist antibody, 2141-V11, by injecting it directly into tumors of 12 patients with metastatic cancers. Six patients saw tumor shrinkage, with two achieving complete remission, including effects on untreated tumors elsewhere in the body. The trial reported only mild side effects, unlike prior CD40 therapies.

Researchers at Uppsala University are launching a new treatment study to help young adults who have had cancer address issues related to sexuality and fertility. Around 40 participants aged 18-39 are involved in a 12-week internet-based program. The study is expected to include a total of about 250 people.

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Researchers at Oregon Health & Science University have created a molecule called SU212 that blocks a key enzyme in triple-negative breast cancer cells. In mouse models, the compound reduced tumor growth and metastasis. The findings offer potential new treatment options for this hard-to-treat form of the disease.

 

 

 

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