Microbioma

Conceptual illustration of gut bacteria producing inflammatory glycogen triggering brain inflammation in C9orf72-linked ALS and FTD, with stool sample comparisons and mouse treatment outcomes.

Study links microbial glycogen in the gut to inflammation in C9orf72-associated ALS and frontotemporal dementia

09 aprile 2026 Riportato dall'IA Immagine generata dall'IA Verificato

Researchers at Case Western Reserve University report that some gut bacteria can make unusually inflammatory forms of glycogen and that this microbial glycogen can trigger immune activity linked to brain inflammation in models of disease tied to the C9orf72 mutation. In patient stool samples, the team found these glycogen forms more often in ALS and C9orf72-related frontotemporal dementia than in healthy controls, and enzymatically breaking down glycogen in the gut improved outcomes in mice.

Mouse study suggests restoring a youthful gut microbiome may curb age-related liver damage and cancer risk

Researchers reported at Digestive Disease Week (DDW) 2026 that older mice given fecal microbiota transplants made from their own preserved, younger-age stool samples showed less liver inflammation and injury—and none developed liver cancer in the experiment.

Study finds coffee improves mood through gut bacteria

07 maggio 2026 Riportato dall'IA

Both caffeinated and decaffeinated coffee can boost mood and mental performance by influencing gut microbes. Researchers found that polyphenols in coffee drive many of these benefits. The findings come from a controlled trial involving 62 healthy adults.

Salute

Western infants lack key gut microbe common elsewhere

Salute

Hidden gut bacteria genus linked to human health

Salute

Doctor hunts for top-quality stool donors in Boston

Faecal transplants enhance kidney cancer treatment results

A small clinical trial shows that faecal microbiota transplants can improve outcomes for kidney cancer patients on immunotherapy drugs. Participants receiving transplants experienced longer cancer stability and greater tumor shrinkage compared to those given placebos. The approach targets the gut microbiome to boost immune responses against tumors.

Study identifies oral microbiome link to obesity

22 gennaio 2026 Riportato dall'IA

Researchers have discovered a unique oral microbiome signature in people with obesity, potentially offering early detection and prevention strategies. The finding, based on saliva samples from Emirati adults, highlights differences in bacteria and metabolic pathways associated with metabolic dysfunction. However, scientists caution that the relationship's causality remains unclear.

Dogs may boost human empathy via microbiome alterations

A study suggests that owning a dog can change the human microbiome in ways that promote empathetic and social behaviors. Researchers found that adolescents with dogs exhibit less social withdrawal and aggression, linked to specific bacteria. Experiments in mice confirmed these microbes enhance prosocial traits.

Studio collega frequenza evacuazioni a rischi per la salute

03 dicembre 2025 Riportato dall'IA

Uno studio dell’Institute for Systems Biology mostra che defecare una o due volte al giorno correla con migliori marcatori di salute. Estremi come stitichezza o diarrea frequente sono legati a problemi biologici sottostanti. I ricercatori hanno esaminato dati di 1.425 adulti per giungere a queste conclusioni.

22 aprile 2026 08:33