Microbiome

Conceptual illustration of gut bacteria producing inflammatory glycogen triggering brain inflammation in C9orf72-linked ALS and FTD, with stool sample comparisons and mouse treatment outcomes.

Study links microbial glycogen in the gut to inflammation in C9orf72-associated ALS and frontotemporal dementia

April 09, 2026 由 AI 报道 AI 生成的图像事实核查

Researchers at Case Western Reserve University report that some gut bacteria can make unusually inflammatory forms of glycogen and that this microbial glycogen can trigger immune activity linked to brain inflammation in models of disease tied to the C9orf72 mutation. In patient stool samples, the team found these glycogen forms more often in ALS and C9orf72-related frontotemporal dementia than in healthy controls, and enzymatically breaking down glycogen in the gut improved outcomes in mice.

Study finds coffee improves mood through gut bacteria

Both caffeinated and decaffeinated coffee can boost mood and mental performance by influencing gut microbes. Researchers found that polyphenols in coffee drive many of these benefits. The findings come from a controlled trial involving 62 healthy adults.

Researchers discover virus in gut bacteria tied to colorectal cancer

April 22, 2026 由 AI 报道

Scientists at the University of Southern Denmark and Odense University Hospital have identified a previously unknown virus inside the common gut bacterium Bacteroides fragilis that appears more frequently in people with colorectal cancer. The finding, detailed by lead researcher Flemming Damgaard, resolves a long-standing paradox since the bacterium is also present in healthy individuals. While the link is strong, the virus's role in causing cancer remains unproven.

健康

Hidden gut bacteria genus linked to human health

健康

Doctor hunts for top-quality stool donors in Boston

科学

Faecal transplants enhance kidney cancer treatment results

Study identifies oral microbiome link to obesity

Researchers have discovered a unique oral microbiome signature in people with obesity, potentially offering early detection and prevention strategies. The finding, based on saliva samples from Emirati adults, highlights differences in bacteria and metabolic pathways associated with metabolic dysfunction. However, scientists caution that the relationship's causality remains unclear.

Maternal emulsifiers alter offspring gut microbiota in mice study

December 26, 2025 由 AI 报道

Researchers have discovered that common food emulsifiers consumed by mother mice can disrupt their offspring's gut microbiome from early life, increasing risks of inflammation, gut disorders, and obesity later on. The study, conducted at Institut Pasteur and Inserm, highlights potential generational health impacts without direct exposure. Findings were published in Nature Communications.

Study links bowel frequency to health risks

A study from the Institute for Systems Biology shows that defecating one or two times a day correlates with better health markers. Extremes like constipation or frequent diarrhea link to underlying biological issues. Researchers examined data from 1,425 adults to reach these findings.

Pregnancy triggers rapid changes in oral microbiome linked to dental risks

November 28, 2025 由 AI 报道

A new study reveals that the oral microbiome undergoes significant shifts during pregnancy, becoming less diverse and potentially more inflammatory. These changes, observed in hundreds of women, may contribute to common dental problems like gum disease and tooth loss. Researchers suggest hormonal and lifestyle factors drive these alterations.

April 13, 2026 06:32