Oncology

Illustration depicting a self-reinforcing SRSF1–AURKA–MYC molecular circuit in pancreatic cancer cells, disrupted by an antisense oligonucleotide therapy.

Study maps self-reinforcing SRSF1–AURKA–MYC circuit in pancreatic cancer cells

10 Mwezi wa kwanza, 2026 Imeripotiwa na AI Picha iliyoundwa na AI Imethibitishwa ukweli

Researchers at Cold Spring Harbor Laboratory report they have identified a three-part molecular circuit involving SRSF1, Aurora kinase A (AURKA) and MYC that helps drive aggressive pancreatic ductal adenocarcinoma. In laboratory models, a splice-switching antisense oligonucleotide designed to alter AURKA splicing disrupted the circuit, reducing tumor-cell viability and triggering programmed cell death.

$154 Billion Transferred to Fund Chile's Oncology Sanitary Alert

One month after the nationwide oncology sanitary alert took effect, Health Minister May Chomali led the signing of a decree transferring $154 billion from the Ministry of Hacienda to the Ministry of Health (Minsal). The funds will exclusively support the Oncology Alert Plan, enhancing public health services' capacity to resolve oncology waiting lists affecting thousands of patients.

Sonora activates cancer-fighting linear accelerator and announces four hospital projects

16 Mwezi wa nne, 2026 Imeripotiwa na AI

Governor Alfonso Durazo Montaño announced the operation of a high-tech linear accelerator at Sonora's State Oncology Center, with an 80 million peso investment, starting this Thursday, April 16. The equipment will double radiotherapy sessions from 11,000 to 22,000 annually and cut wait times from six months to one month, free through IMSS-Bienestar. Four priority hospital infrastructure projects were also unveiled.

Europe

Two oncology patients die in Burgos hospital due to medication dose error

Afya

Scientists identify cell-death enzyme that helps cancer cells survive treatment

Afrika

Servier Egypt launches Tibsovo as first targeted therapy for IDH1-mutated cancers

Excessive sun exposure is most common cause of cancer, says doctor

Oncologist Paulo Hoff warned that excessive sun exposure is the most common cause of cancer, particularly non-melanoma skin cancer. In a course on CasaFolha, he emphasizes the importance of prevention and early diagnosis to boost cure rates. Hoff recommends avoiding the sun between 10am and 2pm and using sunscreen.

Weill Cornell team identifies CD47–TSP-1 signal behind T cell exhaustion; blocking it revives anti-tumor immunity in mice

20 Mwezi wa kumi na moja, 2025 Imeripotiwa na AI Imethibitishwa ukweli

Researchers at Weill Cornell Medicine report that tumors exploit a CD47–thrombospondin-1 signal to push T cells into exhaustion, and that interrupting the interaction restores T cell activity and slows tumor growth in mouse models. The study was published on November 17, 2025, in Nature Immunology.

DNA scar catalog opens paths to overcome cancer drug resistances

Researchers at Spain's National Cancer Research Centre (CNIO) have developed a comprehensive catalog of mutational 'scars' in DNA caused by cancer. This breakthrough, published in Nature, could help bypass resistances to treatments like PARP inhibitors. The study analyzes thousands of tumor samples to identify key genetic patterns.

Vaccine Therapy Progress for Brain Tumors

15 Mwezi wa tisa, 2025 Imeripotiwa na AI Imethibitishwa ukweli

Vaccine therapy for malignant glioma is advancing, with calls for expedited approvals to treat this aggressive brain cancer. The approach has potential to save lives and is part of efforts for rare disease treatments. Early results indicate effectiveness without traditional chemo or radiation.

Jumanne, 10. Mwezi wa tatu 2026, 18:13:08