Onkologi

Illustration depicting a self-reinforcing SRSF1–AURKA–MYC molecular circuit in pancreatic cancer cells, disrupted by an antisense oligonucleotide therapy.

Studi memetakan sirkuit SRSF1–AURKA–MYC penguat diri di sel kanker pankreas

Sabtu, 10 Januari 2026 Dilaporkan oleh AI Gambar dihasilkan oleh AI Fakta terverifikasi

Peneliti di Cold Spring Harbor Laboratory melaporkan bahwa mereka telah mengidentifikasi sirkuit molekuler tiga bagian yang melibatkan SRSF1, Aurora kinase A (AURKA), dan MYC yang membantu mendorong adenocarcinoma duktal pankreas agresif. Dalam model laboratorium, olgonukleotida antisense pengalih sambungan yang dirancang untuk mengubah penyambungan AURKA mengganggu sirkuit tersebut, mengurangi viabilitas sel tumor dan memicu kematian sel terprogram.

$154 Billion Transferred to Fund Chile's Oncology Sanitary Alert

One month after the nationwide oncology sanitary alert took effect, Health Minister May Chomali led the signing of a decree transferring $154 billion from the Ministry of Hacienda to the Ministry of Health (Minsal). The funds will exclusively support the Oncology Alert Plan, enhancing public health services' capacity to resolve oncology waiting lists affecting thousands of patients.

Sonora activates cancer-fighting linear accelerator and announces four hospital projects

Kamis, 16 April 2026 Dilaporkan oleh AI

Governor Alfonso Durazo Montaño announced the operation of a high-tech linear accelerator at Sonora's State Oncology Center, with an 80 million peso investment, starting this Thursday, April 16. The equipment will double radiotherapy sessions from 11,000 to 22,000 annually and cut wait times from six months to one month, free through IMSS-Bienestar. Four priority hospital infrastructure projects were also unveiled.

Eropa

Two oncology patients die in Burgos hospital due to medication dose error

Kesehatan

Para peneliti mengidentifikasi enzim kematian sel yang membantu sel kanker bertahan dari pengobatan

Afrika

Servier Egypt launches Tibsovo as first targeted therapy for IDH1-mutated cancers

Excessive sun exposure is most common cause of cancer, says doctor

Oncologist Paulo Hoff warned that excessive sun exposure is the most common cause of cancer, particularly non-melanoma skin cancer. In a course on CasaFolha, he emphasizes the importance of prevention and early diagnosis to boost cure rates. Hoff recommends avoiding the sun between 10am and 2pm and using sunscreen.

Tim Weill Cornell mengidentifikasi sinyal CD47–TSP-1 di balik kelelahan sel T; memblokirnya menghidupkan kembali imunitas anti-tumor pada tikus

Kamis, 20 November 2025 Dilaporkan oleh AI Fakta terverifikasi

Peneliti di Weill Cornell Medicine melaporkan bahwa tumor mengeksploitasi sinyal CD47–trombospondin-1 untuk mendorong sel T ke kelelahan, dan bahwa mengganggu interaksi tersebut memulihkan aktivitas sel T dan memperlambat pertumbuhan tumor pada model tikus. Studi itu diterbitkan pada 17 November 2025 di Nature Immunology.

DNA scar catalog opens paths to overcome cancer drug resistances

Researchers at Spain's National Cancer Research Centre (CNIO) have developed a comprehensive catalog of mutational 'scars' in DNA caused by cancer. This breakthrough, published in Nature, could help bypass resistances to treatments like PARP inhibitors. The study analyzes thousands of tumor samples to identify key genetic patterns.

Progres Terapi Vaksin untuk Tumor Otak

Senin, 15 September 2025 Dilaporkan oleh AI Fakta terverifikasi

Terapi vaksin untuk glioma ganas sedang maju, dengan panggilan untuk persetujuan dipercepat untuk mengobati kanker otak agresif ini. Pendekatan ini memiliki potensi untuk menyelamatkan nyawa dan merupakan bagian dari upaya untuk pengobatan penyakit langka. Hasil awal menunjukkan efektivitas tanpa kemoterapi atau radiasi tradisional.

10 Maret 2026 18.13