Oncologia

Segui
Illustration depicting a self-reinforcing SRSF1–AURKA–MYC molecular circuit in pancreatic cancer cells, disrupted by an antisense oligonucleotide therapy.
Immagine generata dall'IA

Study maps self-reinforcing SRSF1–AURKA–MYC circuit in pancreatic cancer cells

Riportato dall'IA Immagine generata dall'IA Verificato

Researchers at Cold Spring Harbor Laboratory report they have identified a three-part molecular circuit involving SRSF1, Aurora kinase A (AURKA) and MYC that helps drive aggressive pancreatic ductal adenocarcinoma. In laboratory models, a splice-switching antisense oligonucleotide designed to alter AURKA splicing disrupted the circuit, reducing tumor-cell viability and triggering programmed cell death.

Roche Holding saw its shares drop significantly following the failure of its phase 3 persevERA trial for the breast cancer drug giredestrant to meet its primary endpoint. Despite the setback, the company remains optimistic about the drug's potential in other indications. Analysts view the result as a non-existential hurdle for Roche's broader portfolio.

Riportato dall'IA

La Corte Suprema Federale (Stf) ha approvato all’unanimità un accordo interfederativo che ridefinisce il finanziamento dei farmaci oncologici nel Sistema Unico di Salute (Sus). La decisione stabilisce regole per il rimborso da parte dell’Unione e determina la competenza giudiziaria per le azioni relative a questi trattamenti. L’accordo segue la creazione di una nuova politica di assistenza farmaceutica oncologica.

Clínica Medilaser in Neiva, Huila, is establishing itself as a regional reference center for comprehensive blood cancer management. Led by Dr. Álvaro Eduardo Mondragón Cardona, the institution provides advanced treatments combining chemotherapy and immunotherapy. This allows patients from southern Colombia to receive specialized care without traveling elsewhere.

Riportato dall'IA

Patients at Port Elizabeth Provincial Hospital in Nelson Mandela Bay are facing renewed shortages of essential chemotherapy drugs, leaving pediatric oncology cases vulnerable. The Eastern Cape Department of Health attributes the issue to a suspended account with a key supplier, with negotiations ongoing to restore supply. This marks the third major stockout this year, highlighting persistent procurement challenges.

A new study showed quantum technology achieving 80% tumor shrinkage in brain cancer, published in The Lancet Oncology on September 11, 2025.

Riportato dall'IA

Summit's new drug for lung cancer demonstrated promising results in recent assessments. This development is part of ongoing biotech advancements in oncology. It was reported alongside other health innovations.

 

 

 

Questo sito web utilizza i cookie

Utilizziamo i cookie per l'analisi per migliorare il nostro sito. Leggi la nostra politica sulla privacy per ulteriori informazioni.
Rifiuta