Aging

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Close-up photo of graying hair with overlaid stem cells, illustrating study on stress links to graying and melanoma.

Study links graying hair and melanoma to stress responses in pigment stem cells

Heather Vogel Image generated by AI Fact checked

Japanese researchers report that hair graying and melanoma can arise from the same melanocyte stem cells, which take different paths depending on DNA damage and local signals. Published online October 6, 2025 in Nature Cell Biology, the University of Tokyo-led study outlines a protective differentiation program that promotes graying and how carcinogens can subvert it to favor melanoma.

Study finds life-expectancy gains slowed after 1939

Heather Vogel Fact checked

An analysis of 23 high‑income countries published in PNAS finds the rapid longevity gains of the early 20th century have slowed markedly for cohorts born after 1939, and none of those cohorts are projected to average 100 years of life.

Fatty acid supplementation reverses age-related vision decline in mice

Researchers at UC Irvine have demonstrated that supplementing mice with a specific polyunsaturated fatty acid can restore visual function and reverse signs of cellular aging in the retina. The study targets the ELOVL2 gene, linked to age-related vision loss and macular degeneration. Published in Science Translational Medicine, the findings suggest potential therapies beyond DHA supplementation.

Study shows harmful sperm mutations rise with men's age

New research reveals that genetic mutations in men's sperm, which can lead to diseases in offspring, increase with age due to evolutionary selection within the testes. Scientists used advanced sequencing to analyze sperm from 81 men aged 24 to 75, finding that harmful mutations affect 2 percent of sperm in early 30s men but rise to 4.5 percent in 70-year-olds. The findings, published October 8 in Nature, highlight risks for future generations.

A healthy adult engaging in a long continuous walk in a park, illustrating the link between extended walking bouts and reduced cardiovascular risk.

Longer continuous walks linked to sharply lower heart risk, study finds

Heather Vogel Image generated by AI Fact checked

Walking in bouts of 10–15 minutes or longer was associated with substantially lower cardiovascular risk among adults taking fewer than 8,000 steps a day, with 15‑minute‑plus bouts tied to about a two‑thirds lower risk than very short walks, according to research published in Annals of Internal Medicine.

Northwestern study uncovers why superagers retain youthful memories

Researchers at Northwestern University have spent 25 years studying SuperAgers—people over 80 with memories as sharp as those 30 years younger—revealing key brain traits that resist cognitive decline. Their findings, published in a new perspective article, highlight two protective mechanisms against Alzheimer's-related damage and emphasize the role of social connections. The work could lead to new strategies for preventing dementia.

Study questions U-shaped pattern of happiness over lifespan

A new analysis of UK data challenges the long-held belief that happiness follows a U-shape through life, dipping in midlife before rising again. Researchers found that well-being remains stable or slightly increases with age. This finding, published in Psychological Science, suggests the curve may not be universal.

Online brain training tied to decade‑equivalent boost in cholinergic function, McGill trial finds

Heather Vogel Fact checked

A double‑blind McGill University–led clinical trial reports that 10 weeks of BrainHQ exercises increased a PET marker of cholinergic function in healthy older adults by an amount the authors say roughly offsets about a decade of age‑related decline. The peer‑reviewed study used a specialized tracer to confirm the biochemical change.

Study links gum disease to greater white matter changes in the brain

Heather Vogel Fact checked

Research published October 22, 2025, in Neurology® Open Access reports that older adults with gum disease had more white matter hyperintensities—a marker of tissue damage—than peers without gum disease, even after accounting for other risks.

mRNA Therapy Restores Ovarian Function

A synthetic mRNA therapy successfully regenerated uterine lining in clinical trials, engineering pathways to restore ovarian function in aging populations, as reported on September 8, 2025.

 

 

 

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