Neuroscience

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Glioblastoma erodes skull and disrupts immune system, study reveals

Researchers have discovered that glioblastoma, the most aggressive form of brain cancer, extends beyond the brain by eroding the skull and altering the immune cells in skull marrow. This interaction fuels the cancer's progression and explains why current treatments often fail. The findings, published in Nature Neuroscience, suggest new strategies targeting both brain and bone.

Stanford Breakthrough Alleviates Autism Symptoms in Mice

Scientists at Stanford University have discovered that hyperactivity in the brain's reticular thalamic nucleus may cause autism-like behaviors in mice. By suppressing this overactivity with drugs or neuromodulation, symptoms were reversed in mouse models. This finding suggests potential new therapeutic approaches overlapping with epilepsy treatments.

Human Studies Expand on Transcranial Ultrasound

New human studies on transcranial focused ultrasound (tFUS) demonstrated its ability to alter perception, mood, and decision-making, with expansions reported on September 9, 2025.

Breakthrough Pill Boosts Stroke Brain Recovery

September 15, 2025 Ti AI ṣe iroyin

Researchers have developed a pill that stimulates brain regeneration for stroke recovery by promoting neurogenesis and repairing damage. Tested in preclinical models, the drug replicates rehabilitation effects without extensive therapy. This innovation offers new hope for stroke patients worldwide.

Scientists discover protein that switches off hunger

Researchers have identified how a protein called MRAP2 regulates hunger by transporting the brain receptor MC4R to the cell surface, enhancing appetite-suppressing signals. This finding, from a study involving institutions in Germany, Canada, and the UK, could lead to new obesity treatments. The work was published in Nature Communications.

Scientists uncover brain circuit that overrides chronic pain

Researchers at the University of Pennsylvania have identified a group of brainstem neurons that can suppress chronic pain signals when survival needs like hunger or fear arise. These Y1 receptor neurons in the lateral parabrachial nucleus act as a neural switchboard, prioritizing urgent biological demands over persistent discomfort. The discovery, published in Nature, offers potential new avenues for pain treatments.

New method detects Alzheimer's early using AI brain scans

Scientists have developed an innovative AI-based imaging technique that identifies Alzheimer's disease up to a decade before symptoms emerge. The approach analyzes subtle changes in brain structure from routine MRI scans. This breakthrough, published on October 2, 2025, could transform early intervention strategies.

Scientists identify five distinct sleep profiles and health links

Researchers have pinpointed five types of sleep patterns among young adults, each associated with specific mental health issues and brain activity differences. The study highlights how sleep disturbances, aid use, and short duration connect to cognition, emotions, and behaviors. These profiles offer new insights into sleep's broad impact on well-being.

CRISPR Tool Targets Neuron Gene Repair

September 15, 2025 Ti AI ṣe iroyin

Stanford researchers have created a CRISPR-based technology to target RNA in neurons, enabling repair processes for genetic diseases. The method addresses key challenges in Cas9 delivery and DNA repair. It reveals unique genome editing rules in neurons, paving the way for targeted therapies.

Researchers identify gut bacterium linked to brain health

A new study uncovers a specific gut bacterium that produces a molecule capable of influencing brain function in mice. Led by scientists at the University of California, Berkeley, the research highlights potential new avenues for treating neurological disorders. The findings were published on September 29, 2025, in the journal Nature.