Neuroscience

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Cellular switch discovery offers hope for Parkinson's treatment

Scientists have identified a key cellular regulator called PP2A-B55alpha that balances mitochondrial health, potentially leading to new therapies for Parkinson's disease. In preclinical models, reducing its activity improved motor symptoms and mitochondrial function. The findings, published in Science Advances, could extend to other mitochondrial disorders and cancer.

CRISPR Tool Targets Neuron Gene Repair

15. september 2025 Rapportert av AI

Stanford researchers have created a CRISPR-based technology to target RNA in neurons, enabling repair processes for genetic diseases. The method addresses key challenges in Cas9 delivery and DNA repair. It reveals unique genome editing rules in neurons, paving the way for targeted therapies.

New method detects Alzheimer's early using AI brain scans

Scientists have developed an innovative AI-based imaging technique that identifies Alzheimer's disease up to a decade before symptoms emerge. The approach analyzes subtle changes in brain structure from routine MRI scans. This breakthrough, published on October 2, 2025, could transform early intervention strategies.

Glioblastoma erodes skull and disrupts immune system, study reveals

Researchers have discovered that glioblastoma, the most aggressive form of brain cancer, extends beyond the brain by eroding the skull and altering the immune cells in skull marrow. This interaction fuels the cancer's progression and explains why current treatments often fail. The findings, published in Nature Neuroscience, suggest new strategies targeting both brain and bone.

DMT reduces stroke damage in animal and cell studies

Researchers in Hungary have found that DMT, a natural psychoactive compound, significantly mitigates brain damage from stroke in animal models and cell cultures. The molecule restores the blood-brain barrier and curbs inflammation, potentially complementing current treatments. These discoveries, published in Science Advances, highlight DMT's therapeutic promise amid limited stroke options.

Scientists identify new protein role in brain development

A recent study has revealed how a specific protein influences neural connections during early brain growth. Researchers from the University of California found that disrupting this protein leads to impaired synapse formation in animal models. The discovery could pave the way for better understanding neurodevelopmental disorders.

Breakthrough Pill Boosts Stroke Brain Recovery

15. september 2025 Rapportert av AI

Researchers have developed a pill that stimulates brain regeneration for stroke recovery by promoting neurogenesis and repairing damage. Tested in preclinical models, the drug replicates rehabilitation effects without extensive therapy. This innovation offers new hope for stroke patients worldwide.

Scientists identify five distinct sleep profiles and health links

Researchers have pinpointed five types of sleep patterns among young adults, each associated with specific mental health issues and brain activity differences. The study highlights how sleep disturbances, aid use, and short duration connect to cognition, emotions, and behaviors. These profiles offer new insights into sleep's broad impact on well-being.

Scientists discover brain circuit driving alcohol addiction relapse

Researchers at Scripps Research have identified a brain region that becomes hyperactive in rats, linking alcohol to relief from withdrawal stress and promoting relapse. The paraventricular nucleus of the thalamus plays a key role in this negative reinforcement learning. The findings, published on August 5, 2025, could inform treatments for addiction and related disorders.

New study reveals key mechanism in Alzheimer's disease

Scientists have identified a novel molecular pathway that contributes to the progression of Alzheimer's disease, potentially opening doors to new treatments. The research, published in a leading journal, highlights how specific proteins interact to accelerate brain cell damage. This discovery builds on years of investigation into neurodegenerative disorders.