Neuroscience

Scientific illustration depicting the TMEM175 lysosomal ion channel preventing over-acidification and toxic buildup in neurons, relevant to Parkinson’s disease research.

Study links lysosomal ion channel TMEM175 to protection against over-acidification, with implications for Parkinson’s research

27 марта 2026 Сообщено ИИ Изображение, созданное ИИ Проверено фактами

Researchers at LMU Munich, Bonn-Rhein-Sieg University of Applied Sciences, TU Darmstadt and Nanion Technologies report that the lysosomal ion channel TMEM175 helps prevent excessive acidification inside lysosomes, a malfunction that the team says could contribute to toxic buildup associated with Parkinson’s disease. The findings were reported in the Proceedings of the National Academy of Sciences.

Stroke prompts rejuvenation-like changes in undamaged brain areas

A new study reveals that after a stroke, the undamaged side of the brain can appear biologically younger as it compensates for lost function. Researchers analyzed MRI scans from over 500 stroke survivors worldwide using AI models. The findings suggest neuroplasticity helps explain persistent motor impairments.

Vivid dreams linked to deeper feeling of sleep

26 марта 2026 Сообщено ИИ

Researchers have found that vivid, immersive dreams can make sleep feel deeper and more restorative, even during periods of high brain activity. A study analyzing brain recordings from 44 healthy adults showed that participants reported their deepest sleep after intense dream experiences. The findings challenge traditional views of deep sleep as minimal brain activity.

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Single-celled organism shows capability for Pavlovian learning

Researchers have demonstrated that the single-celled protist Stentor coeruleus can engage in associative learning, similar to Pavlov's experiments with dogs. This finding suggests such cognitive abilities may predate the evolution of brains by hundreds of millions of years. The study highlights unexpected complexity in simple organisms.

New blood test spots Alzheimer's via protein shape changes

12 марта 2026 Сообщено ИИ

Researchers at Scripps Research have developed a blood test that detects Alzheimer's disease by analyzing structural changes in blood proteins. The method identifies differences in three specific proteins, allowing accurate distinction between healthy individuals, those with mild cognitive impairment, and Alzheimer's patients. Published in Nature Aging on February 27, 2026, the findings could enable earlier diagnosis and treatment.

PET brain scans link ketamine’s rapid antidepressant effect to shifts in AMPA receptor availability

A study in Molecular Psychiatry used PET imaging with a new tracer to track changes in AMPA-type glutamate receptors in people with treatment-resistant depression receiving ketamine, reporting that region-specific receptor changes were associated with symptom improvement.

Study links Alzheimer's origins to peripheral inflammation

5 марта 2026 Сообщено ИИ

A new genomic analysis suggests that Alzheimer's disease may begin with inflammation in organs like the skin, lungs, or gut, potentially decades before brain symptoms appear. Researchers analyzed genetic data from hundreds of thousands of people and found risk genes more active outside the brain. This perspective could reshape prevention and treatment strategies.

25 марта 2026, 23:12