Elderly man at dental exam with overlaid brain scan illustrating gum disease's link to brain white matter changes.

Study links gum disease to greater white matter changes in the brain

Heather Vogel AI द्वारा उत्पन्न छवि तथ्य-जाँच किया गया

Research published October 22, 2025, in Neurology® Open Access reports that older adults with gum disease had more white matter hyperintensities—a marker of tissue damage—than peers without gum disease, even after accounting for other risks.

Genetic change protected early humans from lead's evolutionary impact

Researchers have uncovered evidence that ancient hominids were exposed to lead as early as two million years ago, potentially influencing brain evolution. Modern humans possess a unique genetic variant in the NOVA1 gene that shielded them from lead's toxic effects on language development. This discovery, published on October 15, 2025, suggests it gave Homo sapiens an advantage over Neanderthals.

Online brain training tied to decade‑equivalent boost in cholinergic function, McGill trial finds

Heather Vogel तथ्य-जाँच किया गया

A double‑blind McGill University–led clinical trial reports that 10 weeks of BrainHQ exercises increased a PET marker of cholinergic function in healthy older adults by an amount the authors say roughly offsets about a decade of age‑related decline. The peer‑reviewed study used a specialized tracer to confirm the biochemical change.

Neurons use fat—not just sugar—for energy, study ties pathway to rare brain disorder

Heather Vogel तथ्य-जाँच किया गया

Researchers in Australia and Finland report that neurons can fuel themselves with fat as well as sugar, challenging long‑held assumptions about brain energy. The discovery, published in Nature Metabolism, links a lipid‑processing enzyme to a rare hereditary spastic paraplegia and suggests that targeted fatty acid supplements may restore cellular energy in laboratory models.

Microscopic image of alpha-synuclein oligomers in Parkinson's brain tissue, visualized with advanced imaging techniques.

Researchers directly visualize alpha‑synuclein oligomers in human Parkinson’s brain tissue

Heather Vogel AI द्वारा उत्पन्न छवि तथ्य-जाँच किया गया

Scientists in the U.K. and Canada report the first direct visualization and measurement of alpha‑synuclein oligomers—the small protein clusters long suspected of triggering Parkinson’s—in human brain tissue. Using an ultra‑sensitive imaging method, the team found these clusters were larger and more numerous in Parkinson’s than in age‑matched controls, a result published in Nature Biomedical Engineering that may help guide earlier diagnosis and targeted therapies.

Scientists uncover early brain damage before MS symptoms

Researchers at UC San Francisco have found that multiple sclerosis damages the brain years before symptoms appear, by analyzing blood proteins. The study identifies key markers like IL-3 and MOG, potentially enabling earlier diagnosis and prevention. This discovery, published in Nature Medicine, could transform how MS is managed.

Scientists receive $14.2 million NIH award to map the body’s ‘hidden sixth sense’

Heather Vogel तथ्य-जाँच किया गया

A team led by Nobel laureate Ardem Patapoutian at Scripps Research, working with collaborators at the Allen Institute, has secured a five-year, $14.2 million NIH Director’s Transformative Research Award to build what they describe as the first atlas of interoception—the internal sensory system that helps keep breathing, blood pressure and digestion in balance. ([eurekalert.org](https://www.eurekalert.org/news-releases/1101449?utm_source=openai))

UCSF researchers test LSD-based MM120 for generalized anxiety disorder

Heather Vogel तथ्य-जाँच किया गया

UCSF neuroscientist Jennifer Mitchell and collaborators are evaluating MM120, a pharmaceutical form of LSD, as a potential treatment for generalized anxiety disorder. A randomized clinical trial published in JAMA found that a single dose reduced anxiety symptoms versus placebo, with benefits persisting up to 12 weeks in the optimal dose group, according to the study and the drug’s sponsor.

Cognitive ability tied to understanding speech in noisy settings, study finds

Heather Vogel तथ्य-जाँच किया गया

Among people with clinically normal hearing, intellectual ability strongly predicted how well they understood speech amid competing voices, according to a peer-reviewed study from University of Washington researchers.

Northwestern study uncovers why superagers retain youthful memories

Researchers at Northwestern University have spent 25 years studying SuperAgers—people over 80 with memories as sharp as those 30 years younger—revealing key brain traits that resist cognitive decline. Their findings, published in a new perspective article, highlight two protective mechanisms against Alzheimer's-related damage and emphasize the role of social connections. The work could lead to new strategies for preventing dementia.

 

 

 

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