Neuroscience

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Scientists identify new protein role in brain development

A recent study has revealed how a specific protein influences neural connections during early brain growth. Researchers from the University of California found that disrupting this protein leads to impaired synapse formation in animal models. The discovery could pave the way for better understanding neurodevelopmental disorders.

Evolution of human intelligence linked to mental illness vulnerability

Researchers have traced genetic variants in the human genome to reveal that advances in cognitive abilities around 500,000 years ago were soon followed by mutations increasing susceptibility to psychiatric disorders. This suggests a trade-off in brain evolution. The study, published in Cerebral Cortex, analyzed 33,000 genetic variants to build an evolutionary timeline of brain-related traits.

Stanford Breakthrough Alleviates Autism Symptoms in Mice

Scientists at Stanford University have discovered that hyperactivity in the brain's reticular thalamic nucleus may cause autism-like behaviors in mice. By suppressing this overactivity with drugs or neuromodulation, symptoms were reversed in mouse models. This finding suggests potential new therapeutic approaches overlapping with epilepsy treatments.

Playing musical instruments boosts children's reading skills

A new study reveals that children who learn to play musical instruments show significant improvements in reading abilities. The research highlights how musical training enhances phonological awareness, a key component of literacy development. These findings suggest potential benefits for integrating music education in schools.

CRISPR Tool Targets Neuron Gene Repair

September 15, 2025 由 AI 报道

Stanford researchers have created a CRISPR-based technology to target RNA in neurons, enabling repair processes for genetic diseases. The method addresses key challenges in Cas9 delivery and DNA repair. It reveals unique genome editing rules in neurons, paving the way for targeted therapies.

Scientists discover brain circuit driving alcohol addiction relapse

Researchers at Scripps Research have identified a brain region that becomes hyperactive in rats, linking alcohol to relief from withdrawal stress and promoting relapse. The paraventricular nucleus of the thalamus plays a key role in this negative reinforcement learning. The findings, published on August 5, 2025, could inform treatments for addiction and related disorders.

Study identifies potential genetic subtypes of autism

Researchers have proposed that autism spectrum disorder may consist of genetically distinct subtypes, based on an analysis of large-scale genetic data. This finding could lead to more personalized approaches to diagnosis and treatment. The study highlights variations in genetic markers among individuals with autism.

Scientists uncover brain circuit that overrides chronic pain

Researchers at the University of Pennsylvania have identified a group of brainstem neurons that can suppress chronic pain signals when survival needs like hunger or fear arise. These Y1 receptor neurons in the lateral parabrachial nucleus act as a neural switchboard, prioritizing urgent biological demands over persistent discomfort. The discovery, published in Nature, offers potential new avenues for pain treatments.

Breakthrough Pill Boosts Stroke Brain Recovery

September 15, 2025 由 AI 报道

Researchers have developed a pill that stimulates brain regeneration for stroke recovery by promoting neurogenesis and repairing damage. Tested in preclinical models, the drug replicates rehabilitation effects without extensive therapy. This innovation offers new hope for stroke patients worldwide.

Human Studies Expand on Transcranial Ultrasound

New human studies on transcranial focused ultrasound (tFUS) demonstrated its ability to alter perception, mood, and decision-making, with expansions reported on September 9, 2025.