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Realistic illustration of a fatigued young adult overlaid with brain MRI and blood cell visuals highlighting altered ATP energy patterns linked to depression.
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Study links major depression in young adults to altered cellular energy patterns in brain and blood

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Researchers studying young adults with major depressive disorder have reported an unusual energy “signature” in both the brain and immune blood cells: higher ATP-related measures at rest, paired with a reduced ability to increase energy production when demand rises. The findings, published in Translational Psychiatry, may help explain common symptoms such as fatigue and low motivation, though the work is early and based on a small sample.

A multi-state stakeholder consultation in Ahmedabad on Wednesday discussed recommendations from the Lancet Commission report on a citizen-centred health system. Participants highlighted uneven quality of care, fragmented delivery and gaps in mental health services in India's health system.

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Fathers in Sweden were less likely to receive new psychiatric diagnoses during their partner’s pregnancy and in the first months after birth, but diagnoses of depression and stress-related disorders rose by more than 30% toward the end of the child’s first year, according to a large national register study published in JAMA Network Open.

The Naivasha area has seen a surge in suicide cases, with at least 50 people dying between May 2025 and March 3, 2026, mostly men due to family and economic issues. These incidents are linked to depression, substance abuse, and relationship conflicts. Experts and community leaders stress the need for professional help.

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Actor-turned-director Will Ropp makes his feature debut with 'Brian,' a coming-of-age comedy about a high schooler grappling with anxiety and a crush on his teacher. The film premieres at SXSW 2026 in Austin on March 14. Ropp drew from personal experiences to highlight the blurred lines between comedy and tragedy in adolescence.

The Psychiatry Department of Addis Ababa University has released a new book in Amharic to address mental health challenges and stigma in Ethiopia. Edited by leading experts, it compiles reliable information amid rising mental health issues in the country. The Federal Ministry of Health supported the project by funding the printing of 10,000 copies for public distribution.

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Researchers report designing and testing five fluorinated, reversible carbamate derivatives of psilocin—psilocybin’s active metabolite—aimed at reducing acute psychedelic-like effects while preserving key serotonin-receptor activity. In experiments in mice, a lead compound labeled 4e produced lower but longer-lasting brain exposure to psilocin-related activity and triggered fewer head-twitch responses than pharmaceutical-grade psilocybin, according to a study in the Journal of Medicinal Chemistry.

 

 

 

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