Microbiology
South Korean study links cavity-causing mouth bacterium to Parkinson’s-like brain changes in mice
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Researchers in South Korea report evidence that an oral bacterium best known for causing tooth decay can colonize the gut and generate a metabolite that reaches the brain and triggers Parkinson’s-like pathology in mouse experiments. The work, published in Nature Communications, adds to growing evidence that gut microbes and their byproducts may influence neurodegenerative disease processes.
A new study reveals that SAR11, the most abundant bacteria in the world's oceans, may be hindered by their own adaptations to nutrient-poor environments. Under stress, these microbes experience cellular failures that limit their growth, potentially affecting ocean ecosystems amid climate change. Researchers from the University of Southern California highlight this as a key weakness in these dominant lifeforms.
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Researchers report that small doses of the antibiotic cephaloridine can prompt certain gut bacteria to increase production of colanic acid, a microbial polysaccharide previously tied to longer lifespan in laboratory animals. In experiments, treated roundworms lived longer and mice showed shifts in cholesterol or insulin measures associated with aging, with the team arguing the approach works by acting in the gut rather than throughout the body.
Researchers at the University of Vienna have discovered a new type of microbe that oxidizes toxic sulfide using iron minerals, potentially helping to prevent oceanic dead zones. These MISO bacteria convert sulfide into sulfate for energy, reshaping understanding of global sulfur and iron cycles. The findings, published in Nature, highlight microbes' role in maintaining ecological balance.
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Scientists have estimated how quickly certain E. coli strains spread between people and found one lineage with a basic reproduction number comparable to H1N1 swine flu. Drawing on genomic data from the UK and Norway, the analysis—published November 4, 2025, in Nature Communications—models transmission for three ST131 clades and underscores implications for tracking antibiotic-resistant infections.
Researchers at Harvard University have identified specific gut microbiome compositions associated with reduced anxiety in humans. The two-year study, published today, strengthens evidence for the gut-brain connection. This discovery opens doors to microbiome-based mental health interventions.
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Scientists have identified a novel mechanism in soil microbes that enhances long-term carbon sequestration. This breakthrough could help mitigate climate change by locking away more atmospheric CO2. The findings were detailed in a study published on October 1, 2025.
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