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ETH Zurich researchers identify HIF1 as a molecular driver of painful tendon disorders
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Researchers at ETH Zurich report that hypoxia-inducible factor 1 (HIF1) can actively drive harmful tendon changes linked to conditions such as Achilles tendon pain and tennis elbow. In mouse models and in human tendon cells collected during surgery, elevated HIF1 was associated with pathological remodeling that made tendon tissue more brittle and was accompanied by neurovascular ingrowth that may help explain pain.
A new study finds that people who listen to their own choice of music during intense exercise can keep going almost 20 percent longer than when working out in silence. The research, involving cyclists, shows this boost comes without any increase in perceived effort or physical strain.
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The American College of Sports Medicine has released an updated Position Stand on resistance-training prescription for healthy adults, its first update since a 2009 Position Stand. The document is based on an overview of 137 systematic reviews covering more than 30,000 participants and concludes that even small amounts of regular resistance training can improve strength, muscle size, power and physical function.