Heart Disease

A long-term Finnish study has found that inconsistent bedtimes during middle age can nearly double the risk of serious cardiovascular events. People who varied their sleep times widely and spent less than eight hours in bed faced the greatest danger.

1 мая 2026 Сообщено ИИ Проверено фактами

Researchers from the University of Barcelona and the University of Oregon report that short DNA molecules known as polypurine reverse Hoogsteen hairpins (PPRHs) suppressed the PCSK9 gene and reduced blood cholesterol in a mouse model. In transgenic mice carrying the human PCSK9 gene, a single injection of one candidate (HpE12) cut plasma PCSK9 by 50% and total cholesterol by 47% three days later, according to findings published in Biochemical Pharmacology.

A large review of randomized trials indicates that statins do not cause the majority of side effects listed on their labels. Symptoms such as memory problems and depression occurred at similar rates in statin users and those taking placebos. The findings aim to address concerns that have led some patients to avoid these heart-protecting medications.

11 февраля 2026 Сообщено ИИ

New research from Griffith University indicates that maintaining a bedroom at 24°C (75°F) during the night can lower stress responses and improve heart efficiency for people aged 65 and older. The study highlights how heat disrupts sleep recovery, particularly amid rising nighttime temperatures due to climate change. Findings were gathered using wearable trackers and room sensors during an Australian summer.

Only 12% of U.S. adults surveyed said they had heard of cardiovascular-kidney-metabolic (CKM) syndrome, even though nearly 90% have at least one related risk factor, according to a Harris Poll conducted for the American Heart Association. After the term was explained, majorities said it was important to learn more and wanted information on diagnosis and treatment.

5 января 2026 Сообщено ИИ

Researchers in Dresden have discovered that the protein MCL1, known for helping cancer cells evade death, also regulates their energy production through the mTOR pathway. This dual role explains why drugs targeting MCL1 can fight tumors but sometimes harm the heart. The team has developed a dietary approach to mitigate this cardiotoxicity, paving the way for safer therapies.