He Jiankui plans gene editing for Alzheimer’s after prison term

Chinese scientist He Jiankui, who served time in prison for creating the world’s first gene-edited babies, now intends to pursue similar work to combat Alzheimer’s disease. He has criticized Silicon Valley’s efforts in the field as a “Nazi eugenic experiment.” This development revives ethical debates in biotechnology.

In 2018, He Jiankui made headlines by announcing at a scientific conference in Hong Kong that he had produced the world’s first gene-edited babies. The soft-spoken researcher confirmed the reports amid a tense atmosphere in the packed auditorium, adjusting his microphone before addressing the audience.

His actions led to his imprisonment in China for violating regulations on gene editing. Now, years later, He Jiankui is preparing to resume such experiments, this time targeting Alzheimer’s disease with the goal of eradicating it.

He has voiced strong objections to ongoing projects in Silicon Valley, labeling them a “Nazi eugenic experiment.” This perspective underscores the ongoing ethical tensions surrounding gene-editing technologies like CRISPR, which He pioneered in his controversial work.

The announcement, detailed in a recent Wired article, highlights the persistent global divide on the boundaries of genetic intervention. While He’s past work sparked international condemnation for ethical lapses, his renewed ambitions signal a bold push forward in medical applications, though under heightened scrutiny.

相关文章

Scientists at Virginia Tech using CRISPR tools to improve memory in aged rats, illustrating potential for combating cognitive decline.
AI 生成的图像

Virginia Tech team improves memory in aged rats with targeted gene-editing

由 AI 报道 AI 生成的图像 事实核查

Scientists at Virginia Tech report that tuning specific molecular pathways with CRISPR-based tools improved memory in older rats across two peer‑reviewed studies, pointing to possible routes for tackling age‑related cognitive decline.

Health economics specialist Martin Morgenstern stated in an interview that genetic editing will transform medical treatments in the coming decades. According to him, technologies like CRISPR will allow altering specific genes to combat conditions like high cholesterol. This approach promises to be more precise than traditional medications, though it carries inherent risks.

由 AI 报道

在美国度过30年后,世界领先的计算生物学家鲍志荣已全职加入深圳南方科技大学。他以癌症基因组学研究闻名,将在新实验室研究脑回路以洞察自闭症。该举动凸显了中国科研生态的吸引力。

Researchers at UNSW Sydney and St. Jude Children’s Research Hospital report a CRISPR-derived “epigenome editing” approach that turns genes on by removing DNA methylation marks rather than cutting DNA. In cell-based experiments, they show that promoter methylation can directly—and reversibly—silence fetal globin genes, a finding they say helps settle a long-running debate about whether methylation is causal or merely correlated with gene shutdown. The work points to a potential path toward safer therapies for sickle cell disease by reactivating fetal hemoglobin without creating DNA breaks.

由 AI 报道

Researchers at Texas A&M University have developed a chemogenetic system that uses caffeine to activate CRISPR gene editing in cells, potentially aiding treatments for cancer and diabetes. The method allows precise control over gene modifications by consuming small amounts of caffeine from everyday sources like coffee or chocolate. This approach aims to enhance immune responses and insulin production with reversible activation.

A new book by bioethicist Daphne O. Martschenko and sociologist Sam Trejo explores the implications of polygenic scores in genetic testing, highlighting potential inequalities and myths surrounding genetics. Through their 'adversarial collaboration,' the authors debate whether such research can promote equity or entrench social divides. They call for stricter regulation to ensure responsible use.

由 AI 报道

在微米级精密3D打印领域的崛起人才徐振鹏在社交媒体上宣布,从加利福尼亚州的一家初创公司转至中国上海的学术职位。此前,他领导的团队致力于开发芯片生产技术,以实现比传统昂贵设备更快速、更廉价的制造方式。

 

 

 

此网站使用 cookie

我们使用 cookie 进行分析以改进我们的网站。阅读我们的 隐私政策 以获取更多信息。
拒绝