Researchers question vitamin B12 levels and cancer links

Scientists are raising new questions about the relationship between vitamin B12 and cancer risk. While deficiency has long been known to increase dangers, recent studies suggest very high levels may also play a role.

Vitamin B12 supports red blood cell production, DNA repair and nerve function. It occurs naturally in meat, fish, eggs and dairy, with some people relying on fortified foods or supplements. Most individuals on varied diets get enough, though vegans, older adults and those with absorption issues may need extra intake.

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A doctor discussing the risks of biotin supplements with a cancer patient in a medical office, highlighting potential issues with blood tests.
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Doctors warn biotin supplements can interfere with some cancer-related blood tests

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Some cancer patients take biotin supplements hoping to improve hair and nail growth, but specialists at Ohio State University Wexner Medical Center warn that high-dose biotin can interfere with certain blood tests used in cancer monitoring, potentially producing misleading results that could affect follow-up care.

A University of California San Francisco study has linked lower but still normal levels of active vitamin B12 to slower thinking and white matter damage in healthy older adults. The research, published in Annals of Neurology in 2025, suggests current guidelines may miss early neurological risks. Researchers examined 231 participants with an average age of 71.

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A new Japanese study has connected deficiencies in vitamin B12 and folate to increased fatigue and lower motivation in otherwise healthy adults. The research examined blood markers and self-reported symptoms in around 600 participants.

A new study reveals that the MYC protein does more than drive tumor growth. It also repairs DNA damage in cancer cells, allowing some tumors to survive chemotherapy and radiation.

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A UCLA study has found that creatine can enhance the function of dendritic cells, which help activate killer T cells to fight tumors. The research, conducted in mice and human cells, points to potential uses in improving cancer immunotherapy.

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