Healthy Aging

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Illustration depicting healthy elderly individuals with scientific overlays representing the blood protein CtBP2, tied to metabolism and aging markers.

Blood protein CtBP2 tied to metabolism and markers of healthy aging

Heather Vogel Hoton da AI ya samar An Binciki Gaskiya

University of Tsukuba researchers report that CtBP2, a metabolic sensor protein detected in the bloodstream, tracks with age and health status in people—declining with age, remaining higher in members of long‑lived families, and falling in those with advanced diabetic complications.

Naked mole-rats' cGAS mutations enhance DNA repair and longevity

Heather Vogel

Scientists have uncovered how naked mole-rats achieve exceptional longevity through subtle changes in a key immune protein. These mutations in the enzyme cGAS improve DNA repair, potentially explaining why the rodents live up to 40 years. The findings, tested in fruit flies, suggest broader implications for understanding aging.

Mild dietary stress promotes healthier aging in worms

An Ruwaito ta hanyar AI

Researchers at the University of Basel have discovered that specific RNA molecules in nematodes' diets trigger a mild stress response that enhances cellular health and extends healthspan. This process prevents toxic protein buildup associated with aging and diseases like Alzheimer's and Parkinson's. The findings, published in Nature Communications, suggest diet influences how well organisms age.

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