Residu anestesi tertua ditemukan pada peralatan bedah Tiongkok kuno

Residu pada instrumen medis abad ke-15 menunjukkan bahwa dokter Tiongkok menggunakan senyawa tanaman beracun untuk meredakan nyeri selama operasi. Penemuan ini memberikan bukti kimia paling awal mengenai penggunaan anestesi di mana pun di dunia.

Gunting bedah dan pinset yang ditemukan dari makam dokter Xia Quan, yang hidup dari tahun 1348 hingga 1411 di provinsi Jiangsu, mengandung jejak akonitin. Peneliti di Northwest University di Xi’an mengidentifikasi senyawa tersebut menggunakan analisis laser. Instrumen-instrumen tersebut pertama kali digali pada tahun 1974, namun studi kimianya baru dilakukan baru-baru ini.

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Lab illustration of madecassic acid from Centella skincare inhibiting drug-resistant E. coli bacteria.
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Study finds madecassic acid, a Centella compound used in skincare, can inhibit drug-resistant E. coli in lab tests

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Researchers at the University of Kent, working with University College London, report that madecassic acid—a compound derived from the medicinal herb Centella asiatica and widely used in skincare—can inhibit the growth of antibiotic-resistant E. coli by targeting a bacterial respiratory system not found in humans or other animals.

Experiments suggest Neanderthals could have applied birch tar, found at their sites, as an antiseptic for wounds due to its antibiotic properties. Researchers replicated ancient production methods and tested the tar against bacteria causing skin infections. The findings build on evidence of Neanderthals using medicinal plants.

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Chemists at the University of Bristol analyzed the air around tiny fragments of Egyptian mummies to identify volatile organic compounds linked to embalming materials. The study, covering remains from 3200 BC to 395 AD, found 81 distinct compounds from oils, resins, beeswax, and bitumen. These clues show mummification practices grew more complex over time.

Chinese scientists have used an AI model to determine the chemical make-up of the moon's far side, offering new insights into one of lunar science's enduring mysteries. The findings add to insights from China's historic Chang'e-6 mission to the lunar far side in 2024.

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Hong Kong customs officers seized 6.5kg of suspected drugs worth HK$3.4 million (US$433,800) and arrested two men in separate operations earlier this week. The Customs and Excise Department said the first arrest took place at Hong Kong International Airport, where 3.1kg of suspected ketamine was found in a 43-year-old man's baggage from Bangkok; the second involved 1.7kg each of suspected cocaine and methamphetamine in Yau Ma Tei.

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