Ilmuwan temukan angin internal dalam sel yang terkait dengan penyebaran kanker

Para peneliti di Oregon Health & Science University telah mengidentifikasi aliran cairan tersembunyi di dalam sel yang dengan cepat mengangkut protein ke tepi depan, menantang pandangan tradisional tentang pergerakan seluler. Penemuan yang dilakukan selama eksperimen di kelas ini dapat menjelaskan mengapa beberapa sel kanker menyebar secara agresif. Temuan ini diterbitkan dalam Nature Communications.

Catherine Galbraith dan James Galbraith, peneliti di Oregon Health & Science University, mengungkap mekanisme seluler tersebut saat memimpin kursus neurobiologi di Marine Biological Laboratory di Massachusetts. Dengan menggunakan laser untuk melacak pergerakan protein, mereka mengamati pita gelap aktin terlarut yang tak terduga yang meluncur ke tepi depan sel. 'Kami melakukannya untuk bersenang-senang dan kemudian menyadari bahwa ini memberi kami cara untuk mengukur sesuatu yang sebelumnya tidak dapat diukur,' kata Cathy Galbraith. Hal ini mengungkapkan aliran cairan terarah, yang diibaratkan seperti angin pasat, yang mendorong protein lebih cepat daripada yang dimungkinkan oleh difusi acak saja. James Galbraith menambahkan, 'Sel benar-benar mengikuti arus.'

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