Cientistas descobrem ventos internos em células ligados à disseminação do câncer

Pesquisadores da Oregon Health & Science University identificaram fluxos de fluido ocultos dentro das células que transportam proteínas rapidamente para a borda frontal, desafiando visões tradicionais sobre o movimento celular. A descoberta, feita durante um experimento em sala de aula, pode explicar por que algumas células cancerígenas se espalham de forma agressiva. Os resultados foram publicados na Nature Communications.

Catherine Galbraith e James Galbraith, pesquisadores da Oregon Health & Science University, descobriram o mecanismo celular enquanto ministravam um curso de neurobiologia no Marine Biological Laboratory, em Massachusetts. Usando um laser para rastrear o movimento das proteínas, eles observaram uma inesperada faixa escura de actina solúvel correndo em direção à borda frontal da célula. 'Nós fizemos isso meio que por diversão e então percebemos que isso nos dava uma maneira de medir algo que não era possível medir antes', disse Cathy Galbraith. Isso revelou fluxos de fluido direcionados, comparados aos ventos alísios, que impulsionam as proteínas mais rapidamente do que a difusão aleatória permitiria. James Galbraith acrescentou: 'As células realmente seguem o fluxo'.

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