Study links vitamin B12 and folate to fatigue

A new Japanese study has connected deficiencies in vitamin B12 and folate to increased fatigue and lower motivation in otherwise healthy adults. The research examined blood markers and self-reported symptoms in around 600 participants.

Researchers led by Professor Hiroaki Kanouchi at Osaka Metropolitan University analyzed blood levels of homocysteine, folate, and vitamin B12. They also assessed fatigue using the Chalder Fatigue Scale and a Visual Analog Scale while controlling for age, sleep, workload, and diet.

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