دراسة تجد أن سرطان الميلانوما ينتشر بشكل أكبر في منتصف العمر

31 مايو، 2026

من إعداد الذكاء الاصطناعي

أظهر بحث جديد من مركز فوكس تشيس للسرطان أن سرطان الميلانوما ينتشر بشراسة أكبر في الفئران متوسطة العمر مقارنة بالفئران الصغيرة أو الطاعنة في السن. ويبدو أن هذا النمط مرتبط بتغيرات تطرأ على نوع معين من الخلايا المناعية بمرور الوقت.

عرض الباحثون النتائج في الاجتماع السنوي للجمعية الأمريكية لأبحاث السرطان. وبلغ انتشار السرطان ذروته في الفئران متوسطة العمر، بينما ظل أقل في الفئران الصغيرة وانخفض مجدداً في الفئران الطاعنة في السن. وأشار ميتشل فين، الباحث الرئيسي، إلى أن معظم الدراسات المخبرية تستخدم فئراناً صغيرة السن فقط، مما يحد من فهم كيفية تصرف السرطان لدى المرضى الأكبر سناً.

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Researchers at Marshall University report that microscopic particles found in the gut lumen—known as exosomes—differ between young and old mice and can influence metabolism and gut-barrier function when transferred between animals. The findings, published in the journal Aging Cell, suggest these particles may help drive biological changes associated with aging, though the work is preclinical.

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Mouse study suggests restoring a youthful gut microbiome may curb age-related liver damage and cancer risk

10 مايو، 2026 من إعداد الذكاء الاصطناعي تم التحقق من الحقائق

Researchers reported at Digestive Disease Week (DDW) 2026 that older mice given fecal microbiota transplants made from their own preserved, younger-age stool samples showed less liver inflammation and injury—and none developed liver cancer in the experiment.

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Study shows cloned mice accumulate harmful mutations

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A 20-year experiment cloning mice has revealed that clones develop significantly more genetic mutations than naturally reproduced mice, accumulating to fatal levels after multiple generations. Researchers led by Teruhiko Wakayama at Yamanashi University in Japan found over 70 mutations per clone generation on average, three times higher than in controls. The findings, published in Nature Communications, raise concerns for applications in farming, conservation and de-extinction efforts.

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دراسة تجد أن سرطان الميلانوما ينتشر بشكل أكبر في منتصف العمر

مقالات ذات صلة

Study links gut “luminal exosomes” to age-related inflammation and metabolic decline in mice

UCLA scientists reverse liver damage in mice by removing zombie cells

Mouse study suggests restoring a youthful gut microbiome may curb age-related liver damage and cancer risk

Study of nearly 500 cat tumors finds cancer-gene overlaps with humans and dogs

Study finds olive oil fat speeds pancreatic cancer in mice

Stiffening cancer cells boosts car t-cell therapy in mice

Johns Hopkins identifies KLF5 gene fueling pancreatic cancer spread

Study shows cloned mice accumulate harmful mutations

Study links loss of MHC class I on tumors to CD4+ T cell-driven ferroptosis

RSV infection in mice prevents breast cancer spread to lungs

Scientists uncover HOXD13 as master switch in melanoma growth

Study of young lung cancer patients finds unexpectedly high diet-quality scores; researchers probe possible pesticide exposure

UCSF study explains severe flu and COVID in older adults

UNIGE researchers unveil AI tool predicting cancer metastasis

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