CRISPR
UC San Diego researchers describe a gene-drive-like CRISPR system designed to reduce antibiotic resistance in bacteria
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Researchers at the University of California San Diego report they have developed a second-generation CRISPR-based “Pro-Active Genetics” system, called pPro-MobV, that is designed to spread between bacteria and disable antibiotic-resistance genes, including inside hard-to-treat biofilms.
Caribou Biosciences discussed progress on its off-the-shelf CAR-T therapies during a presentation at the Bank of America Global Healthcare Conference on May 13. Chief executive Rachel Haurwitz highlighted Phase I data for two programs that target lymphoma and multiple myeloma.
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Researchers at Rice University have found that the protein PEX11 not only helps peroxisomes divide but also regulates their size during early plant development. In Arabidopsis seedlings, PEX11 mutants developed abnormally large peroxisomes lacking internal vesicles that normally curb growth. The mechanism appears conserved across species, as yeast Pex11 restored normal function in plant mutants.
Conservationists are divided over a proposed moratorium on genetic modification of wildlife at an upcoming International Union for Conservation of Nature meeting. While some groups seek a pause to assess risks, others argue that technologies like CRISPR are essential for saving endangered species. The vote could influence funding and policies worldwide.