CRISPR

Nobel Prize-winning scientist Jennifer Doudna has cofounded Aurora Therapeutics, a startup focused on developing personalized gene-editing treatments for rare diseases. The company plans to leverage CRISPR technology and a new FDA regulatory pathway to bring these therapies to market. This initiative builds on recent successes in custom treatments that have saved lives.

January 05, 2026 由 AI 报道 事实核查

Researchers at UNSW Sydney and St. Jude Children’s Research Hospital report a CRISPR-derived “epigenome editing” approach that turns genes on by removing DNA methylation marks rather than cutting DNA. In cell-based experiments, they show that promoter methylation can directly—and reversibly—silence fetal globin genes, a finding they say helps settle a long-running debate about whether methylation is causal or merely correlated with gene shutdown. The work points to a potential path toward safer therapies for sickle cell disease by reactivating fetal hemoglobin without creating DNA breaks.

Scientists have used CRISPR to edit a single gene in pigs, making them fully resistant to classical swine fever, a contagious disease that devastates livestock. This breakthrough could enhance animal welfare, boost productivity, and reduce emissions. The same edit may protect cattle and sheep from related viruses.

October 07, 2025 由 AI 报道

Conservationists are divided over a proposed moratorium on genetic modification of wildlife at an upcoming International Union for Conservation of Nature meeting. While some groups seek a pause to assess risks, others argue that technologies like CRISPR are essential for saving endangered species. The vote could influence funding and policies worldwide.