CRISPR
UC San Diego researchers describe a gene-drive-like CRISPR system designed to reduce antibiotic resistance in bacteria
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Researchers at the University of California San Diego report they have developed a second-generation CRISPR-based “Pro-Active Genetics” system, called pPro-MobV, that is designed to spread between bacteria and disable antibiotic-resistance genes, including inside hard-to-treat biofilms.
Researchers have identified the gene NANOG as the key switch that initiates the developmental program resulting in cells forming a human body. The finding came from precise DNA edits to fertilized human eggs using CRISPR base editing.
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Researchers in New York have tested an improved gene-editing method on healthy human embryos donated for research. The study shows mixed success in making precise DNA changes while avoiding some unintended mutations.
A novel grafting method could allow gene editing in plants like cocoa, coffee, and avocados that are currently hard to modify. Researchers have demonstrated that engineering rootstocks to produce CRISPR components can edit shoots from non-modified plants. This approach promises broader application of precise genetic improvements for agriculture.
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Scientists have used CRISPR to edit a single gene in pigs, making them fully resistant to classical swine fever, a contagious disease that devastates livestock. This breakthrough could enhance animal welfare, boost productivity, and reduce emissions. The same edit may protect cattle and sheep from related viruses.