Longevity

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Naked mole-rats' cGAS mutations enhance DNA repair and longevity

Heather Vogel

Scientists have uncovered how naked mole-rats achieve exceptional longevity through subtle changes in a key immune protein. These mutations in the enzyme cGAS improve DNA repair, potentially explaining why the rodents live up to 40 years. The findings, tested in fruit flies, suggest broader implications for understanding aging.

Global Innovator Summit Announced by NAM

The National Academy of Medicine announced its fifth annual virtual Global Innovator Summit, set for September 29 and 30, 2025. The event will feature Catalyst Award winners sharing their health longevity innovations.

Study finds life-expectancy gains slowed after 1939

Heather Vogel 사실 확인됨

An analysis of 23 high‑income countries published in PNAS finds the rapid longevity gains of the early 20th century have slowed markedly for cohorts born after 1939, and none of those cohorts are projected to average 100 years of life.

Nutrient Sensing Breakthrough in Trials

AI에 의해 보고됨

Human trials on dysregulated nutrient sensing via the mTOR pathway showed significant results, including a 50% reduction in infections after an 8-week treatment. The study by Joan Mannick demonstrated lasting effects for a year. This advances longevity and health research.

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