Omfattande studie har kartlagt genetiska kopplingar till endometrios över olika härkomster

8 juni 2026

Rapporterad av AI

En omfattande analys av data från över en miljon kvinnor har identifierat hundratals gener kopplade till endometrios. Forskningen kopplar även tillståndet till inflammation, kolesterolreglering och förändringar i tarmfloran.

Forskare kombinerade data om genetik, proteiner och mikrobiom från 14 globala biobanker. De fann 58 genomiska regioner förknippade med endometrios, varav 27 tidigare okända, och identifierade 314 specifika gener. Tre av dessa genetiska regioner framträdde endast när genom från personer med afrikanskt ursprung undersöktes. Många av de starkaste genkopplingarna rörde immunfunktion, inflammation och cellrörelse. Studien kopplade även endometrios till lägre nivåer av Bifidobacteriaceae-bakterier och till faktorer som ökar kardiovaskulära risker. Shefali Setia-Verma vid University of Pennsylvania noterade att år av obehandlad inflammation kan bidra till mer omfattande hälsoproblem. Nilufer Rahmioglu vid University of Oxford menar att inkluderandet av flera olika ursprungsgrupper är en styrka, även om ytterligare studier krävs för att bekräfta behandlingsmål.

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Omfattande studie har kartlagt genetiska kopplingar till endometrios över olika härkomster

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