Semprotan hidung Texas A&M membalikkan penuaan otak dalam sebuah studi

Para peneliti di Texas A&M University telah mengembangkan semprotan hidung yang tampaknya dapat membalikkan aspek penuaan otak hanya setelah dua dosis. Perawatan tersebut mengurangi peradangan dan memulihkan fungsi memori pada model selama berbulan-bulan setelahnya. Temuan ini diterbitkan dalam Journal of Extracellular Vesicles.

Terapi eksperimental ini menggunakan vesikel ekstraseluler yang dimuati dengan microRNA yang diberikan melalui semprotan hidung. Pendekatan ini menargetkan peradangan kronis di otak yang dikenal sebagai neuroinflammaging dan memulihkan fungsi mitokondria dalam sel. Dr. Ashok Shetty memimpin tim tersebut bersama Dr. Madhu Leelavathi Narayana dan Dr. Maheedhar Kodali. Studi ini menerima dukungan dari National Institute on Aging dan menghasilkan pengajuan paten di Amerika Serikat.

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