Spray nasal da Texas A&M reverte envelhecimento cerebral em estudo

Pesquisadores da Universidade Texas A&M desenvolveram um spray nasal que parece reverter aspectos do envelhecimento cerebral após apenas duas doses. O tratamento reduziu a inflamação e restaurou a função da memória em modelos por meses após a aplicação. As descobertas foram publicadas no Journal of Extracellular Vesicles.

A terapia experimental utiliza vesículas extracelulares carregadas com microRNAs administradas por meio de um spray nasal. Essa abordagem combate a inflamação crônica no cérebro, conhecida como neuroinflamação, e restaura a função mitocondrial nas células. O Dr. Ashok Shetty liderou a equipe com o Dr. Madhu Leelavathi Narayana e o Dr. Maheedhar Kodali. O estudo recebeu apoio do National Institute on Aging e resultou em um pedido de patente nos Estados Unidos.

Artigos relacionados

Scientist in lab studying mouse with DNA and brain inflammation overlays representing Alzheimer’s drug research.
Imagem gerada por IA

Experimental drug reduced DNA damage and inflammation in an Alzheimer’s mouse model, King’s College London says

Reportado por IA Imagem gerada por IA Verificado

Scientists at King’s College London report that an experimental compound, KCL-286, repaired markers of DNA damage and lowered brain inflammation in a mouse model of Alzheimer’s disease. The team says the drug—originally developed for spinal cord injury—has already completed Phase 1 safety and tolerability testing in humans, which could speed plans for further clinical studies.

A widely studied anti-aging treatment triggered significant brain damage in mice, according to new research from the University of Connecticut. The drug combination dasatinib plus quercetin caused myelin loss and changes resembling those seen in multiple sclerosis. The findings raise questions about its use in longevity studies and off-label therapies.

Reportado por IA Verificado

Researchers from the Institute for Bioengineering of Catalonia and collaborating institutions report that engineered “supramolecular” nanoparticles restored aspects of blood-brain barrier function in Alzheimer’s-model mice, rapidly lowering brain amyloid-β and producing improvements on behavioral and memory tests.

Researchers have identified declining levels of phosphatidylcholine as a key driver of age-related mitochondrial dysfunction. The discovery, made at the Leibniz Institute on Aging in Germany, shows that boosting this lipid can restore youthful mitochondrial function in laboratory models.

Reportado por IA Verificado

A three-year analysis following 3,966 adults ages 19 to 94 found measurable improvements in a multidimensional brain-health score among participants who used brief daily online training tools, including people in their 80s and beyond.

quinta-feira, 16 de julho de 2026, 16:37h

Drug restores senescent cell clearance in aging mice

sexta-feira, 19 de junho de 2026, 11:40h

Faecal transplant boosts brain plasticity in older mice

terça-feira, 26 de maio de 2026, 14:54h

USC researchers identify compounds targeting Alzheimer’s brain inflammation

domingo, 24 de maio de 2026, 01:40h

Brain protein decline linked to aging in mice study

terça-feira, 05 de maio de 2026, 14:45h

Hong Kong researchers develop world-first nasal spray for stroke aid

Este site usa cookies

Usamos cookies para análise para melhorar nosso site. Leia nossa política de privacidade para mais informações.
Recusar