Declínio de proteína cerebral está ligado ao envelhecimento em estudo com camundongos

Um estudo de 2023 descobriu que a queda nos níveis da proteína menina no hipotálamo impulsiona múltiplos sinais de envelhecimento em camundongos. Restaurar a proteína ou suplementar com o aminoácido D-serina melhorou a memória e outros indicadores.

Pesquisadores da Universidade de Xiamen, na China, mostraram que os níveis de menina caem drasticamente em uma parte específica do hipotálamo conforme os camundongos envelhecem. Quando reduziram a menina em animais mais jovens, os camundongos desenvolveram inflamação cerebral, ossos mais frágeis, pele mais fina, pior equilíbrio, perda de memória e expectativa de vida mais curta.

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