El declive de una proteína cerebral vinculado al envejecimiento en un estudio con ratones

Un estudio de 2023 descubrió que la caída en los niveles de la proteína menina en el hipotálamo provoca múltiples signos de envejecimiento en ratones. Restaurar esta proteína o suplementar con el aminoácido D-serina mejoró la memoria y otros indicadores.

Investigadores de la Universidad de Xiamen en China demostraron que los niveles de menina disminuyen drásticamente en una parte específica del hipotálamo a medida que los ratones envejecen. Cuando redujeron la menina en animales más jóvenes, los ratones desarrollaron inflamación cerebral, huesos más débiles, piel más fina, peor equilibrio, pérdida de memoria y una esperanza de vida más corta.

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