E. coli modificada produz gadusol, um composto natural de proteção solar

Pesquisadores modificaram bactérias para fabricar gadusol, uma substância com proteção UV encontrada em ovos de peixes. O avanço pode apoiar o desenvolvimento de protetores solares transparentes e ecológicos. O trabalho foi liderado por uma equipe da Universidade Jiangnan, na China.

Uma equipe liderada por Ping Zhang inseriu genes de peixe-zebra em Escherichia coli. As bactérias adquiriram as enzimas necessárias para produzir gadusol, que ocorre naturalmente em pequenas quantidades nos ovos de peixes-zebra, salmões e esturjões, bem como em corais. Usando pequenas moléculas de RNA e ajustando as condições de crescimento, os cientistas elevaram a produção em quase 93 vezes, atingindo 4,2 gramas por litro de meio, em comparação com os 45,2 miligramas por litro obtidos anteriormente.

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